1. Department of Pathology R3 NKY Case 1

13. Large intestine, total colectomy: Intestinal pseudo-obstruction with decreased interstitial cells of Cajal Appendix, total colecotomy: No specific change Ileum, total colecotomy: Fibrous adhesion Diagnosis

14. GI motility disorder Neural disorder Muscular disorder Interstitial cells of Cajal (ICC) A/W systemic disease Infection Brief Review

15. Pacemaker cells conrolling SM contraction Coordinators in the neural control of SM Esophagus, stomach, small and large bowel Distribution; Submucosa, intramuscular, myenteric plexus ICC

16. Hirshcsprung disease Interstitial neuronal dysplasia Description of following structure 1) Ganglion 2) Nerve 3) Interstitial cells of Cajal Template for Reporting GI Motility Disorder

17. Department of Pathology R3 NKY Case 2

25. Stomach, distal gastrectomy: Tubular adenocarcinoma, poorly differentiated 1) Location: Gastro-jejunal anastomosis site 2) Tumor gross type: Early gastric carcinoma, type IIa + IIb 3) Histologic type by Lauren classification: Intestinal 4) Tumor size: 0.8 cm x 0.6 cm 5) Depth of invasion: Tumor invades muscularis mucosae (pT1a) 6) Margins of resection: No tumor identified at proximal and distal resection margins (safety margin: proximal 3.0 cm, distal 4.0 cm) 7) Lymphatic invasion: Not identified 8) Vascular invasion: Not identified 9) Regional lymph nodes: No metastasis in 15 regional lymph nodes (0/15, pN0) (perigastric: 0/11, omental: 0/2, LN7: 0/1, LN8/; 0/1) 10) Additional pathologic findings: Gastric cystica superficialis Diagnosis