1. Development Aspects of Blood Anatomy and Physiology

2. Fetal Development Circulatory system develops early –Blood flows by day 28 Many sites of blood formation –Liver –Spleen –Red marrow at 7 months HgF has higher affinity for O 2 than HgA

3. Jaundice Fetal cells replaced by normal RBC’s IF baby can’t break down old cells well Bilirubin accumulated Infant becomes jaundiced UV radiation breaks it down

4. Homeostatic Imbalances Genetic –Sickle cell –Hemophilia –Hemolytic disease of newborn Dietary –Vitamin K needed by the liver to make factors –Pernicious Anemia Lack of B12

5. Imbalances Age increases risk –Leukemia –Anemia –Clotting disorders Linked to circulatory problems or immune deficiencies

6. Ch 10 Homework 1-12 multiple Choice 13,15-17, 20-29, 32-33 Test Monday!