1. Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Significance of Non-Type 1 Anterior Early Repolarization in Patients With Inferolateral Early Repolarization Syndrome J Am Coll Cardiol. 2013;62(17):1610-1618. doi:10.1016/j.jacc.2013.05.081 ECGs in the ERS(A)-Group (A) At baseline, a 42-year-old man exhibited J waves (arrows) followed by ascending ST-segments in leads I, aVL, V4, and V5 in the standard (4th) recording and in leads V2 and V3 in the third (3rd) and second (2nd) intercostal recordings. After pilsicainide injection, all J waves in limb lead disappeared with appearance of S waves and an R-wave in lead aVR. Saddleback ST-segment elevation with slightly augmented J waves (broad arrows) were also noted in V2 in the high intercostal spaces. He experienced an electrical storm 4 years after implantable cardioverter-defibrillator (ICD) insertion. (B) At baseline, electrocardiograms (ECGs) of a 51-year-old man exhibited J waves followed by horizontal or descending ST segments in leads II, III, and aVF (arrows). There was no sign of coved or saddleback ST-segment elevation in any chest leads. After injection of 50-mg pilsicainide, saddleback ST-segment elevation (broad arrows) appeared in leads V1 and V2 in the second and third intercostal spaces with augmented J waves (broad arrows) preceded by newly appearing S waves in leads II, III, and aVF (shown in expanded ECGs). He showed spontaneous VF 1 month after ICD insertion. (C) A 31-year-old man had J waves (arrows) followed by ascending ST-segments in leads I, II, III, aVF, V4, V5, and V6 in the baseline standard (4th) ECG. Furthermore, upward/downward spiky notches ≥1 mm were identified at the end of QRS to early ST-segment in leads V1 and V2 only in the high costal (3rd and 2nd ) recordings. After pilsicainide injection, J waves in leads I, aVL, and V6 were augmented (broad arrows), although other J waves were unchanged or slightly attenuated. He experienced an electrical storm 1 month after ICD insertion. Figure Legend:

2. Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Significance of Non-Type 1 Anterior Early Repolarization in Patients With Inferolateral Early Repolarization Syndrome J Am Coll Cardiol. 2013;62(17):1610-1618. doi:10.1016/j.jacc.2013.05.081 ECGs in the ERS(B)-Group In the baseline electrocardiograms (ECGs) of this 39-year-old man, J waves were present in leads II, III, aVF, and V6(arrows). After pilsicainide injection, they all disappeared with appearance of S waves. The ECGs in leads V1 to V3 during standard and high costal recording remained normal, even after pilsicainide injection. This patient experienced no ventricular fibrillation recurrence. Figure Legend:

3. Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Significance of Non-Type 1 Anterior Early Repolarization in Patients With Inferolateral Early Repolarization Syndrome J Am Coll Cardiol. 2013;62(17):1610-1618. doi:10.1016/j.jacc.2013.05.081 Kaplan-Meier Analysis of Documented VF Kaplan-Meier analysis of lethal arrhythmic events (documented ventricular fibrillation [VF]) during follow-up according to the clinical subgroups—inferolateral early repolarization combined with non-type 1 anterior early repolarization (ERS[A]-group), pure inferolateral early repolarization without anterior early repolarization (ERS[B]-group), Brugada syndrome (BS)-group, and idiopathic ventricular fibrillation (IVF)-group—in patients with a prior VF. Figure Legend:

4. Date of download: 6/28/2016 Copyright © The American College of Cardiology. All rights reserved. From: Significance of Non-Type 1 Anterior Early Repolarization in Patients With Inferolateral Early Repolarization Syndrome J Am Coll Cardiol. 2013;62(17):1610-1618. doi:10.1016/j.jacc.2013.05.081 Kaplan-Meier Analyses of Lethal Arrhythmic Events Kaplan-Meier analyses of lethal arrhythmic events during follow-up according to the clinical subgroups—ERS(A)-group, BS with inferolateral ER group, and BS without inferolateral ER group—in patients with a prior VF. Abbreviations as in Figure 3. Figure Legend: