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Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease by Monica L. Hulbert,

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Presentation on theme: "Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease by Monica L. Hulbert,"— Presentation transcript:

1 Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease by Monica L. Hulbert, Robert C. McKinstry, JoAnne L. Lacey, Christopher J. Moran, Julie A. Panepinto, Alexis A. Thompson, Sharada A. Sarnaik, Gerald M. Woods, James F. Casella, Baba Inusa, Jo Howard, Fenella J. Kirkham, Kofi A. Anie, Jonathan E. Mullin, Rebecca Ichord, Michael Noetzel, Yan Yan, Mark Rodeghier, and Michael R. DeBaun Blood Volume 117(3):772-779 January 20, 2011 ©2011 by American Society of Hematology

2 Children with SCD receiving regular blood transfusion therapy for secondary prophylaxis of strokes. Monica L. Hulbert et al. Blood 2011;117:772-779 ©2011 by American Society of Hematology

3 Survival free of new overt or silent cerebral infarcts in children with SCD while on transfusion therapy for secondary stroke prophylaxis. Monica L. Hulbert et al. Blood 2011;117:772-779 ©2011 by American Society of Hematology

4 Survival free of detection of new silent cerebral infarcts in children with SCD while on transfusion therapy for secondary stroke prophylaxis. Monica L. Hulbert et al. Blood 2011;117:772-779 ©2011 by American Society of Hematology

5 Survival free of second overt strokes in children with SCD while on transfusion therapy for secondary stroke prophylaxis. Monica L. Hulbert et al. Blood 2011;117:772-779 ©2011 by American Society of Hematology


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