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What we know Halogen (Grp 7) Yellow-green gas Elec. Config: [Ne] 3s 2 3p 5 3 rd most Electronegative Strong Oxidizer Commonly: NaCl salt.

Published byEarl Kelly Modified over 8 years ago

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Presentation on theme: "What we know Halogen (Grp 7) Yellow-green gas Elec. Config: [Ne] 3s 2 3p 5 3 rd most Electronegative Strong Oxidizer Commonly: NaCl salt."— Presentation transcript:

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2 What we know Halogen (Grp 7) Yellow-green gas Elec. Config: [Ne] 3s 2 3p 5 3 rd most Electronegative Strong Oxidizer Commonly: NaCl salt

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4 Used in warfare

5 Chlorine in Biology ? Gastric Gland Lumen ---- Proximal Tube Lumen

6 Kidney Nephron

7 Cystic Fibrosis (mucoviscidosis) Congenital Absence of vas Deferens Meconium ileus Pancreatitis (CFTR-type) Gall stones (CFTR-type) Cholera Cl-related Disease

8 Cystic Fibrosis

9 Defined: Inherited Dx. characterized by the buildup of thick, sticky mucus Most common fatal genetic disease Prevalence : 1 in 2,500 babies (UK) 1 in 3,600 babies (Ca) Affects many organs - sp: Lung, pancreas, skin Etiology: CFTR mutation

10 The CFTR protein is a channel protein that controls the flow of H 2 O & Cl − ions

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13 Improved Life Expectancy with medical advancements

14 CF Initial Signs Salty Skin Baby does not pass stool when born Dehydration Frequent coughing Unnaturally Thick sputum Frequent Resp. infections (e.g. sinusitis, bronchitis) Diarrhea or bulky, foul-smelling, greasy stools Aspermia, Female infertility

15 Clubbing

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