1. The Biopharmaceutical Industry – Protecting Investment through Sustainable policy Barry O’Leary February 23 rd 2012

2. Current Impact of FDI gh KEY FDI IMPACTS ON THE IRISH ECONOMY - €115 BN Exports - 250,000 Jobs in Total - 65% of Corporation Tax - €19 BN Expenditure - €7 BN Payroll - 68% of Business RD&I expenditure WORLD LEADERS CHOOSE IRELAND - 8 of the top 10 in ICT - 9 of the top 10 in Pharmaceuticals - 17 of the top 25 in Medical Devices - More than 50% of the world’s leading Financial Services firms - 10 Top “Born on the Internet” companies - 3 of the Top 5 Games Companies

3. IDA Focus Business Model Focus Global Services High-end Manufacturing Research, Development & Innovation Life Sciences - Pharma/Biopharma & - Medical Devices Information & Communications Technology Financial Services Content Industry, Consumer & Business Services Diversified Industries and Engineering CleanTech Sectors

4. IDA focus across industry segments Leading MNCs 2 nd Tier Emerging Companies

5. What attracts FDI to Ireland? Talent, Technology, Track Record (operational excellence), Tax, the ease of doing Business, EU Access, English speaking are building blocks… Sector / Activity / Country Specific Ireland’s Value Proposition - Needs Constant Enhancement Example – Biopharmaceuticals; - FDA Track Record - National Institute for Bioprocessing and Research Training (NIBRT) - Technology Centres - SFI Initiatives - Strategic Sites - Cluster Impact - Financial Incentives - Regulatory Environment

6. Ireland – Major Life Sciences Hub 9 of the top 10 Pharma companies 17 of top 25 Med Tech companies 44,000 jobs Exports of €51 billion per annum Numerous sub-suppliers and service providers

7. Recent Investments

8. BioPharma in Ireland

9. Transformation Challenge 146,000 - FDI Direct Employees / 250,000 impact Productivity Targets Cost Pressures IDA Transformation Supports; Technology uplift Skills uplift Process development Product Development / R&D Energy Efficiency

10. World Competitiveness Rankings IBM PLI Global Location Trends Report 2011;  2 nd ranked destination by jobs per 100,000 inhabitants  1 st ranked destination by value* of Investment projects * a combination of Productivity, value-added, knowledge intensity and occupational profile composition IMD World Competiveness Yearbook 2011  1 st in the world for corporate taxes  1 st for business legislation for foreign investors  1 st for the availability of skilled labour  2 nd in the world for consumer price inflation  3 rd for direct investment flows inward  3 rd for availability of finance skills  4 th in the world for labour productivity  4 th for exports of commercial services.

11. IBM PLI Global Location Trends Report 2011 2 nd ranked destination by jobs per 100,000 inhabitants

12. IBM PLI Global Location Trends Report 2011 1 st ranked destination by value* of Investment projects

13. Pipeline Outlook Development and Manufacturing - Biologics R&D Small Molecule Shared Services – beyond single function