1. Overview of glucose metabolism © Michael Palmer 2014

2. The place of glycolysis in glucose degradation © Michael Palmer 2014

3. Alternate structures of D-glucose © Michael Palmer 2014

4. Reactions in glycolysis © Michael Palmer 2014

5. The phosphate groups in ATP are shielded from nucleophilic attack © Michael Palmer 2014

6. The catalytic mechanism of hexokinase © Michael Palmer 2014

7. Hexokinase envelopes its substrates to prevent ATP hydrolysis © Michael Palmer 2014

8. Phosphohexose isomerase performs acid-base catalysis © Michael Palmer 2014

9. Glyceraldehyde-3-phosphate dehydrogenase carries out covalent catalysis © Michael Palmer 2014

10. Structure and redox chemistry of NAD + and NADP + © Michael Palmer 2014

11. Pyruvate Kinase © Michael Palmer 2014

12. Energy-rich functional groups in substrates of glycolysis ● the enolphosphate in PEP ● the carboxyphosphate in 1,3-bisphosphoglycerate ● the thioester in the active site of glyceraldehyde-3- dehydrogenase

13. Regeneration of cytosolic NAD + under aerobic conditions © Michael Palmer 2014

14. Under anaerobic conditions, NAD + is regenerated by lactate dehydrogenase © Michael Palmer 2014

15. Ethanolic fermentation in yeast serves a dual purpose © Michael Palmer 2014

16. Kinetics of glucose transport by facilitated diffusion © Michael Palmer 2014

17. GLUT transporters in different tissues vary in their affinity for glucose © Michael Palmer 2014

18. Reaction velocities of hexokinase and glucokinase © Michael Palmer 2014