1. Lesson 6

2.  Textbooks  Repro  Page 8-9 of ppq  Comparison sheet

3.  To know about fibrous proteins  Explain the term quaternary structure  Describe the properties and functions of fibrous proteins  Including collagen, keratin & elastin

4.  Draw the structure of a protein and label it in as much detail as you can

5.  Proteins made of more than one polypeptide chain  May have an inorganic component  Can’t function without all components  E.g. Haemoglobin and collagen - Explain the term quaternary structure

6.  3 polypeptides  Wound together  Rope like structure  Triple helix  Hydrogen bonded  Flexible  Every 3 rd amino acid is glycine  Small  Closely packed when wound together  High amounts of proline and hydroxyproline  Repel each other, adding stability - Describe the properties and functions of fibrous proteins

7.  Complete the table using page 104-105 in the book and your flipped learning - Describe the properties and functions of fibrous proteins

8. Feature Collagen Haemoglobin Type of biological molecule Protein Protein Type of protein Fibrous Globular Main function Strength Carry oxygen Inorganic component No Haem group (Iron) Amino acid sequence Every 3 rd amino acid is glycine (small) High amounts of proline and hydroxyproline Variable Structure Only 1 type of polypeptide chain Microfibrils 2 types of polypeptide chains Where found in the body Connective tissue Red blood cells - Describe the properties and functions of fibrous proteins

9.  Found in hair, skin & nails  Large amounts of cysteine  Lots of strong disulfide bonds  Less disulfide bonds means more flexible - Describe the properties and functions of fibrous proteins

10.  Found in elastic fibres  E.g. walls of blood vessels  Lots of soluble tropelastin molecules cross linked  To create large, stable, insoluble molecule  Can stretch and relax  Have alternating areas of hydrophobic and lysine- rich  Cross links caused by hydrophobic interactions and covalent bonds involving lysine - Describe the properties and functions of fibrous proteins

11.  Past Paper Questions  Q3 Jan 2008

14.  Past paper question Jan 11 Q7

17.  Draw the structure of a protein and label it in as much detail as you can

18.  Complete the summary table