1. A.k.a : Muramidase OR N-acetylmuramide glycanhydrolase
Lysozyme
A.k.a :
Muramidase OR
N-acetylmuramide glycanhydrolase

2. Lysozyme An enzyme found naturally in • egg white • human tears
• saliva (as well as other body fluids)
Capable of destroying the cell walls of certain bacteria.
Acts as a mild antiseptic.

3. Amino Sequence
Fig 5. Lysozyme amino acid sequence alignment for five organisms (Dmelanogaste-fly, EcoligsnAA-E. coli, GgallusgsnAA-chicken, HsapiensgsnA-human, and Mmusculusgsn-mouse). Number to the left and right of the sequences and above each sequence group indicate amino acid number. Letters represent amino acids, with dashes (-) inserted to maximize sequence alignment. Black boxes indicate amino acid conservation.

4. Structure
Made with 117 amino acid residues and has a heterogeneous sequence.
1REM
133L
1IWV
Quaternary Structure (4°)
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5. Function
Lysozyme attacks peptidoglycans and hydrolyzes the glycosidic bond that connects N-acetylmuramic acid with the fourth carbon atom of N-acetylglucosamine. It does this by binding to the peptidoglycan molecule in the binding site within the prominent cleft between its two domains.
Peptidoglycans- sugars & amino acids that form a mesh-like layer outside the plasma membrane of bacteria, forming the cell wall.
Hydrolysis- Decomposition of a chemical compound by reaction with water, such as the dissociation of a dissolved salt or the catalytic conversion of starch to glucose.

6. Present in other Organisms
• bacteriophages (viruses that infect bacteria)
• bacteria
• plants
• animals

7. Misc…
• Lysozyme was first identified and named by Alexander Fleming, who recognized its bacteriolytic properties. (1922)
• Bottlefed babies are 3 times likely to have diarrheal disease, because they lack lysozyme in their diet... [its in breast milk!] Lysozyme is a natural form of protection from pathogens.
Bacteriolysis -destruction or dissolution of bacterial cells

8. Works Cited:
Yikrazuul. "Lysozyme." Wikipedia. N.p., 14 Oct Web. 14 Oct < wiki/Lysozyme>.
Muraki, M., et al. "HUMAN LYSOZYME WITH MAN-B1,4-GLCNAC COVALENTLY ATTACHED TO ASP53." RCSB Protein Data Bank. N.p., 14 Oct Web. 14 Oct < explore.cgi?pdbId=1rem>.
3. Secretlens. "Drool." DeviantArt. N.p., 15 July Web. 14 Oct <
4. funkipunk . “Tears Speak." DeviantArt. N.p., 13 Nov Web. 14 Oct <
5. Caothicart . “Dark Pikachu." DeviantArt. N.p., 10 June Web. 14 Oct <
Chueh, Luke . “I ASKED FOR SCRAMBLED.” LukeChueh N.p., Web. 14 Oct <
Stryer L Biochemistry. 4th ed. New York: W.H. Freeman and Company. p 372.
"MacDNAsis Analysis of Lysozyme Genbank search results." Davidson College. N.p., 30 Nov Web. 14 Oct < MacDNAsis.html>.