1. Date of download: 7/1/2016 Copyright © 2016 American Medical Association. All rights reserved. From: UV-A1 Phototherapy vs Clobetasol Propionate, 0.05%, in the Treatment of Vulvar Lichen Sclerosus: A Randomized Clinical Trial JAMA Dermatol. 2014;150(6):621-627. doi:10.1001/jamadermatol.2013.7733 Flow Diagram of the Study Figure Legend:

2. Date of download: 7/1/2016 Copyright © 2016 American Medical Association. All rights reserved. From: UV-A1 Phototherapy vs Clobetasol Propionate, 0.05%, in the Treatment of Vulvar Lichen Sclerosus: A Randomized Clinical Trial JAMA Dermatol. 2014;150(6):621-627. doi:10.1001/jamadermatol.2013.7733 Portable UV-A1 Sellas Irradiation Unit (System Dr Sellmeier) Used in This StudyAll patients randomized to UV-A1 phototherapy received a portable irradiation unit to take home in order to perform the radiation therapy in a comfortable environment. Figure Legend:

3. Date of download: 7/1/2016 Copyright © 2016 American Medical Association. All rights reserved. From: UV-A1 Phototherapy vs Clobetasol Propionate, 0.05%, in the Treatment of Vulvar Lichen Sclerosus: A Randomized Clinical Trial JAMA Dermatol. 2014;150(6):621-627. doi:10.1001/jamadermatol.2013.7733 Outcome Measures Used in This StudyA, Total clinician’s score (TCS) by visit. B, Mean Skindex-29 scores by visit. C, Mean visual analog (VAS) scores for burning and/or pain by visit. D, Mean VAS scores for itching by visit. T0 indicates baseline; T1, after 1 month of therapy; T2, after 2 months of therapy; T3, at end of therapy; and F3, 3 months after the end of therapy. Error bars indicate the standard error of the mean. Figure Legend:

4. Date of download: 7/1/2016 Copyright © 2016 American Medical Association. All rights reserved. From: UV-A1 Phototherapy vs Clobetasol Propionate, 0.05%, in the Treatment of Vulvar Lichen Sclerosus: A Randomized Clinical Trial JAMA Dermatol. 2014;150(6):621-627. doi:10.1001/jamadermatol.2013.7733 Treatment of Vulvar Lichen Sclerosus With Topical Clobetasol Propionate, 0.05%, Ointment and UV-A1 PhototherapyA, Extensive genital lichen sclerosus. B, Significant clinical improvement with complete clearance of all erosions and fissures following topical treatment with clobetasol ointment. C, Widespread genital lichen sclerosus. D, Marked clinical improvement with clearance of perilesional erythema and reduction of hyperkeratoses and erosions. The clinical pictures are representative of the outcome of the study, showing a significant improvement following therapy with clobetasol ointment (A and B) and UV-A1 phototherapy (C and D). Figure Legend: