1. Diauxic Shift Fermentation: energy-converting metabolism without the involvement of an exogenous oxidizing agent(typically anaerobic) Respiration: energy-converting metabolism with the involvement of an exogenous oxidizing agent(typically aerobic)

2. Yeast Metabolism

3. Gene Clustering 16 Chromosomes Do genes upregulated during the diauxic shift display chromosomal clustering? Or random distribution ?

4. Expression of proteins

7. Expected and Control Distributions Control suggests “background” gene clustering

11. ????????????? Variance due to a decrease in sample size? Intrachromosomal clustering trends? Replication of results? Micro (clumping of a few groups of related genes)? Or macro (clustering of a set of divergent genes related through a broadly-defined function)?