1. MEKON & HOBO Java Frameworks for building Ontology-Driven Applications Current use cases:  Almost (!) products:  Knowledge-driven clinical documentation system  Web-based recruitment application  Early prototypes:  Sepsis prediction system  Clinical trials design/design-retrieval system

2. Very, very briefly MEKON based around a generic frames model  Simple frame/slot based representation Plug-in framework allows incorporation + integration of:  Ontology-like knowledge sources  Associated reasoning mechanisms OWL + DL based plug-ins are provided HOBO extends MEKON Enables creation of domain-specific object models, bound to appropriately populated frames models Instantiations of object models operate in-tandem with instantiations of bound frames models

3. Also come with… Instance Store mechanisms, delivered via plug-in framework Current plug-ins based on: 1. OWL constructs + DL reasoning 2. RDF (Stardog or Jena) + SPARQL 3. The XML database BaseX Model Explorer GUI, enables model developer to: 1.Browse frames model 2.Explore dynamic behaviour of specific instantiations  As provided via external reasoners or object model 3.Exercise instance store (store instances / execute queries)

4. For software developers MEKON & HOBO 1.Provide layered architecture:  Structured means of combining:  Generic knowledge sources + reasonners  Domain-specific processing  Configurable via creation/customisation of plug-ins 2.Handle much of the dirty work:  Lower-level interaction with ontologies + reasoners  Intermediate-level processing 3.Provide client access via appropriate APIs:  Generic frames model  Domain-specific object models

5. MEKON enables the creation of a skeleton application, without having to write a single line of code OWL Ontology + DL Reasoner + MEKON Framework + MEKON Configuration File + Model Explorer  Skeleton OWL-Driven Application For ontology developers

6. Come and see MEKON & HOBO demo