1. CHAPTER 8 RNA: Transcription and Processing CHAPTER 8 RNA: Transcription and Processing Copyright 2008 © W H Freeman and Company

2. CHAPTER OUTLINE 8.1 RNA 8.2 Transcription 8.3 Transcription in eukaryotes 8.4 Functional RNAs

3. RNA polymerase in action Chapter 8 Opener

4. RNA

5. Eukaryotic mRNA moves from nucleus to cytoplasm Figure 8-1

6. Unnumbered figure pg 297

7. Unnumbered figure pg 298

8. The four ribonucleotides found in RNA Figure 8-2

9. Transcription

10. Opposite DNA strands can serve as template for RNA Figure 8-3

11. Overview of transcription Figure 8-4

12. Many RNAs can be simultaneously transcribed from a gene Figure 8-5

13. Sequences of DNA and transcribed RNA Figure 8-6

14. Promoter sequences in E. coli Figure 8-7

15. Transcription initiation in prokaryotes Figure 8-8

16. Elongation and termination of transcription Figure 8-9

17. Elongation and termination of transcription Figure 8-9a

18. Elongation and termination of transcription Figure 8-9b

19. A bacterial transcription-termination site Figure 8-10

20. Transcription in eukaryotes

21. Prokaryotic and eukaryotic transcription and translation compared Figure 8-11

22. Transcription initiation in eukaryotes Figure 8-12

23. Transcription initiation in eukaryotes Figure 8-12 part 1

24. Transcription initiation in eukaryotes Figure 8-12 part 2

25. Cotranscriptional processing of RNA Figure 8-13

26. Cotranscriptional processing of RNA Figure 8-13a

27. Cotranscriptional processing of RNA Figure 8-13b

28. Cotranscriptional processing of RNA Figure 8-13c

29. Complex patterns of eukaryotic mRNA splicing Figure 8-14

30. Functional RNAs

31. Conserved sequences related to intron splicing Figure 8-15

32. Spliceosome assembly and function Figure 8-16

33. Spliceosome assembly and function Figure 8-16 part 1

34. Spliceosome assembly and function Figure 8-16 part 2

35. Reactions in exon splicing Figure 8-17

36. Self-splicing reaction Figure 8-18

37. Self-splicing reaction Figure 8-18 part 1

38. Self-splicing reaction Figure 8-18 part 2

39. Small RNAs were the breakthrough of the year Figure 8-19

40. Petunia flowers demonstrating cosuppression Figure 8-20

41. Mechanism of action of RNAi Figure 8-21

42. A way to generate double-stranded RNA in a cell Figure 8-22