1. Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Incidence and Predictors of Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Undergoing Implantable Cardioverter- Defibrillator Implantation for Primary Prevention J Am Coll Cardiol. 2011;58(14):1485-1496. doi:10.1016/j.jacc.2011.06.043 Prophylactic ICD Implantation in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients (A) Age at time of defibrillator implantation. (B) Interval between implantable cardioverter-defibrillator (ICD) implantation and the first appropriate discharge. (C) Number of appropriate ICD discharges. Figure Legend:

2. Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Incidence and Predictors of Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Undergoing Implantable Cardioverter- Defibrillator Implantation for Primary Prevention J Am Coll Cardiol. 2011;58(14):1485-1496. doi:10.1016/j.jacc.2011.06.043 Appropriate ICD Therapy in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients (A) Kaplan-Meier analysis of cumulative survival from any appropriate implantable cardioverter-defibrillator (ICD) interventions. (B) Kaplan-Meier analysis of survival free of ventricular fibrillation/ventricular flutter (VF/VFL). Figure Legend:

3. Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Incidence and Predictors of Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Undergoing Implantable Cardioverter- Defibrillator Implantation for Primary Prevention J Am Coll Cardiol. 2011;58(14):1485-1496. doi:10.1016/j.jacc.2011.06.043 Risk Factors for Appropriate ICD Therapy Cumulative rate of first appropriate discharge stratified according to inducibility at electrophysiologic study (EPS) (A), the presence of nonsustained ventricular tachycardia (NSVT) (B), premature ventricular complex (PVC) count >1,000 on Holter monitoring (C), and proband status (D). Figure Legend:

4. Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Incidence and Predictors of Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Undergoing Implantable Cardioverter- Defibrillator Implantation for Primary Prevention J Am Coll Cardiol. 2011;58(14):1485-1496. doi:10.1016/j.jacc.2011.06.043 Holter Monitoring and ICD Therapy (A) Relationship between the number of patients experiencing appropriate implantable cardioverter-defibrillator (ICD) therapy and patient groups stratified according to increasing premature ventricular complex (PVC) count into equal pentiles. (B) Cumulative survival free of appropriate ICD therapy among patient groups (pentiles) stratified according to increasing PVC count and unadjusted hazard ratio (HR) for these patient groups demonstrating progressively increasing risk with worsening PVC burden. Figure Legend:

5. Date of download: 7/6/2016 Copyright © The American College of Cardiology. All rights reserved. From: Incidence and Predictors of Implantable Cardioverter-Defibrillator Therapy in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Undergoing Implantable Cardioverter- Defibrillator Implantation for Primary Prevention J Am Coll Cardiol. 2011;58(14):1485-1496. doi:10.1016/j.jacc.2011.06.043 Incremental Risk of Appropriate ICD Therapy With Multiple Risk Factors Cumulative survival free of appropriate implantable cardioverter-defibrillator (ICD) therapy (A) and ICD therapy for VF/VFL (B) stratified by the number of risk factors (the risk factors considered are inducibility at electrophysiologic study, the presence of nonsustained ventricular tachycardia, Holter premature ventricular complex count >1,000/24 h, and proband status). Figure Legend: