1. Chapter 11 Advanced Genetics Codominance Multiple Allele Traits Polygenic Inheritance Lethal Alleles Epistatic Alleles

2. Incomplete Dominance Traits appear to "blend" in offspring RR x WW RW (pink) Show: Pink x Red Pink x Pink White x White

3. Figure 11.14 This illustrates another style of "letters" to denote genotypes R1 and R2 Don’t let letter conventions throw you off on the AP test.

4. ROAN COW - What happens when you cross a white and a red cow? Roan is codominant - both alleles R and W are expressed

5. What happens when two Roan Cows are Crossed?

6. Blood Types - Multiple Alleles

7. When doing blood type crosses, you will need to know whether at type A or B person is heterozygous or homozygous. Type O's are automatically OO and type AB is automatically AB. Crosses are performed the same as any other. Show Crosses: A B x A O A O x B O A A x A B

8. Determine the genotypes of these aliens given that the trait is controlled by multiple alleles.

9. Polygenic Traits - controlled by many genes ● Each allele intensifies or diminishes the phenotype. ● Variation is continuous or quantitative (adding up) - also called quantitative inheritance ● Seed Color in wheat - aabbcc, Aabbcc, AaBbcc, AaBbCc, AABbCc, AABBCC (light, intermediate colors, dark) ● In humans - hair color, height, skin color

10. Pg 197 Polygenic Inheritance AABBCC x aabbcc (P) AaBbCc x AaBbCc (F1) Seven Possible Phenotypes in the F2

11. Figure 11.16

12. Figure 11.17

13. Environment and Phenotype Temperature, water, food sources can have an affect on how a gene is expressed Rabbits have a gene that codes for darker pigments - this gene is more active at low temperatures. Parts of the body that are colder will develop the darker pigmentation - ears and feet

14. Figure 11.18b

15. SIAMESE CATS

16. Sex Linked Genes Genes located on the X chromosome are inherited with that X. When doing crosses you must include the sex chromosomes in your cross. Use superscript letters for the allele. Example: In fruit flies, eye color is a sex linked trait. Red is dominant to whit e. Females Males X R X R X R Y X R X r X r Y X r

17. White eyed male x red eyed female: X r Y x X R X R Red eyed male x white eyed female: X R Y x X r X r

18. EPISTATIC ALLELES In labrador retriever, coat color is determined by one gene with four different alleles. Five different colors result from the combinations of these alleles. Black is dominant to chocolate B or b Yellow is recessive and epistatic (when present, it blocks the expression of the black and chocolate alleles) E or e

19. Black Lab BBEE BbEE BBEe BbEe Chocolate Lab bbEE bbEe Yellow Lab BBee Bbee bbee

20. 1. A black lab (BBEe) x yellow lab (bbee) 2. A chocolate lab (bbEe) x black lab (BbEe)

21. 3. Two black labs (BBEE x BbEe)