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Published byAugust Webb Modified over 8 years ago
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HUMAN TRAITS
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PEDIGREE * CHART OF RELATIONSHIPS WITH A FAMILY; DETERMINES GENOTYPES OF TRAITS OF MEMBERS
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http://projects.cbe.ab.ca/Diefenbaker/Biology/Bio%20Website%20Final/notes/classical/Image18.gif
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http://fig.cox.miami.edu/~cmallery/150/mendel/sf17x3.jpg
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Autosomal Recessive Diseases Inheritance when 2 parents who share a recessive gene for a disease pass this gene to an offspring. Usually, parents are heterozygous for this trait & are unaware of their potential for passing on this disease. Examples: Tay-Sachs Disease, Albinism, Cystic Fibrosis, PKU http://bioinf.may.ie/degree/lectures/first/i2_2.gif
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RECESSIVE ALLELE DISORDERS 1. ALBINISM (aa) = NO SKIN PIGMENT
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2. CYSTIC FIBROSIS – EXCESS LUNG MUCUS
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3. PKU –HIGH PHENYLALANINE (AMINO ACID) IN TISSUES. http://depts.washington.edu/pku/images/food_bullseye.jpg
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4. TAY-SACHS – HIGH LIPIDS IN BRAIN
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AUTOSOMAL DOMINANT DISORDERS *the inheritance of a single copy of a defective gene that “over-rides” normal gene !
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1. HUNTINGTON’S DISEASE – NEUROLOGICAL http://www.about-dementia.com/articles/images/HuntingtonsPedigree.gif
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CO-DOMINANT DISORDERS 1. SICKLE-CELL DISORDER – RED BLOOD CELLS
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