1. EBCR Week 2

2. Case Scenario A woman 31 yo, married, came to GP with recurrent postcoital pervaginal bleeding since 3 weeks ago. Doctor considered that the woman had cervical cancer. Regarding the limitation of diagnostic tools, doctor used visual inspection with acetic acid. The result was positive. The patient was diagnosed with cervical cancer.

3. Question Is VIA sensitive enough to diagnose cervical cancer in reproductive women?

4. PATIENT /PROBLEM INTER-VENTIONCOMPARISONOUTCOME Reproductive women VIAPapsmearCervical Cancer PICO: Is VIA sensitive enough to diagnose cervical cancer in reproductive women ? Type of Question: Diagnosis Type of study/methodology: Controlled Trials; Systematic Review/Meta Analysis of Controlled Trials

5. Search Strategy DatabaseSearch strategyhitsSelection articles PubmedCervical cancer AND (pap smear OR cytology) AND visual inspection AND acetic acid NOT HIV NOT serology Limits 23 CochraneCervical cancer AND (pap smear OR cytology) AND visual inspection AND acetic acid 82

6. Flow Chart Cervical cancerAND Acetic acid Visual inspection wPap smear OR cytology AND PubmedCochrane 152 8 Exclusion: HIV, serology Inclusion: Humans, free full text, english 145 23 Filtering Doubles 30 Screening title abstract 13 Reading full text Useful articles: 9 10 Full text availability Search date: June 1, 2011 *All decisions were made by consensus or at least 2 authors

7. THANK YOU