Presentation is loading. Please wait.

Presentation is loading. Please wait.

Characterization of a Large Mumps Outbreak Among Adolescents in Jerusalem, Israel 2009-2010 in Communities Associated with Jewish Communities in New York.

Published byAugust Welch Modified over 8 years ago

Similar presentations

Presentation on theme: "Characterization of a Large Mumps Outbreak Among Adolescents in Jerusalem, Israel 2009-2010 in Communities Associated with Jewish Communities in New York."— Presentation transcript:

1 Characterization of a Large Mumps Outbreak Among Adolescents in Jerusalem, Israel 2009-2010 in Communities Associated with Jewish Communities in New York Mumps outbreak in Jerusalem affecting mainly male adolescents. Stein-Zamir C, Shoob H, Abramson N, Tallen-Gozani E, Sokolov I, Zentner G. Euro Surveill. 2009 Dec 17;14(50). 1 Chen Stein-Zamir MD MPH Jerusalem District Health Office Ministry of Health Israel

2 Mumps in Israel 1977-2008 Year Number of cases Rate / 100,000 Data Source: Dep. Epidem. And ICDC, Ministry of Health, Israel

3 Incidence Rate /100,000 by age-group, Israel:1977-2004 Data Source: Dep. Epidem. And ICDC, Ministry of Health, Israel

4 Mumps in Israel 1997-2008 Year Number of cases Data Source: Dep. Epidem. And ICDC, Ministry of Health, Israel

5 Mumps Vaccine schedule in Israel  MMR schedule: 12 months, 6 years of age.  Since 2008 MMRV (Priorix-Tetra, GSK)  Composition: Jeryl Lynn strain 5

6 Mumps outbreak in Jerusalem, Israel 16 Sept. 2009 -31 Mars 2010: 1862 reported cases in Jerusalem > 2600 reported cases of mumps in Israel 6 Data Source: Jerusalem District Health Office, Ministry of Health, Israel

7 Mumps Outbreak Case Definition case definition: an illness with acute onset of unilateral / bilateral tender, self- limited swelling of the parotid / other salivary glands, lasting at least 2 days, and without other apparent cause. Probable case: a case that meets the clinical case definition without laboratory confirmation + epidemiologically linked to a clinically compatible case Confirmed case: a case that 1) meets the clinical case definition or occurs in a patient with a clinically compatible illness and 2) is either laboratory confirmed or is epidemiologically linked to a confirmed case. 7

8 Cases’ Characteristics  Males: 1218/1862 (65.4%).  > 90% members of ultra-orthodox Jewish communities.  1232 (66.2%) religious colleges and schools.  Geographic distribution: - Jerusalem 61.1% - Other cities 39.9% 8 Data Source: Jerusalem District Health Office, Ministry of Health, Israel

9 Case ascertainment  Positive mumps IgM antibody: 104 patients.  Positive mumps IgG antibody: 121 patients.  Positive real-time RT-PCR in urine: 5 patients.  Genotype G 5 identified.  The others- diagnosed on the basis of clinical features and epidemiologic association. 9 Data Source: Jerusalem District Health Office, Ministry of Health, Israel

10 Number of cases Mumps outbreak - Jerusalem epidemic curve - September 2009- March 2010 September OctoberNovemberDecemberJanuaryFebruaryMarch Data Source: Jerusalem District Health Office, Ministry of Health, Israel

11 Number of cases Age group Mumps outbreak in Jerusalem 2009-10 cases age-group and gender distribution Mean age=14.4± 8.9 Median= 12.9 11 Data Source: Jerusalem District Health Office, Ministry of Health, Israel

12 Schools Total number of casesNumber of schoolsNumber of Mumps cases per school 142 1 2891062-4 268445-9 1471310-14 128815-19 188820-30 70230+ 1232323Total 12 Data Source: Jerusalem District Health Office, Ministry of Health, Israel

13 Vaccination status Parental report. Review of vaccination cards. Verification from health-care providers. 13

14 Number of cases Age group Mumps outbreak - Jerusalem 2009-10 cases age & vaccination status 14 241 cases: vaccine status unknown Data Source: Jerusalem District Health Office, Ministry of Health, Israel

15 Vaccine coverage: Israel  MMR1 in 2006 among children at 2Y :.96%  MMR 1in 1992 – 82.3 %. 15

16 Epidemiologic Links 1.Contact with yeshiva students from New York. 2.Visited Israel during the High Holidays, Sept. 2009. 3.Some reported to have recently had mumps. 16

17 Mumps Outbreak: NY & Jerusalem 58%61%Age 7–18 years 82%91%Age > 6 years 12.9 y15 yMedian age 4 months- 66 years3 months- 90 yearsAge range 65.4%76%Male (%) 74%75%2 doses MMR vaccine 1.8%1.3%Hospitalization Update: mumps outbreak - New York and New Jersey, June 2009-January 2010. Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep. 2010 Feb 12;59(5):125-9. Data Source: Jerusalem District Health Office, Ministry of Health, Israel

18 Prevalence of mumps antibodies 19991997/19981987Population group 82.3%92.5%18-19y olds 83.3%94.1%18-19y olds 68.5%18-19y olds Foreign-born 86.1%18-19y olds Israeli born 77%Age-stratified population sample 59%10-13y olds 18 1.Amital H, Weiss Y. Medax 2001 – Summary of the medical corps session. IMAJ 2002:4:153-5 2.Huerta et al Vaccine. 2006 Sep 11;24(37-39):6300-3 3.Muhsen et al Epidemiol Infect. 2008 May;136(5):688-93.

19 Control measures  Investigation: Relevant schools  Student vaccination status.  Referral for completion of MMR.  Isolation.  Routine Vaccination – Coverage.  Information: Circulated to all HMOs in the District, and to the public via the mass media. 19

20 Why?  Vaccine failure?  Failure to vaccinate?  Waning immunity?  Accumulation of susceptibles?  Setting, high risk for transmission?  Characteristics of mumps infection of immunity?  Misdiagnosis of mumps? 20

Download ppt "Characterization of a Large Mumps Outbreak Among Adolescents in Jerusalem, Israel 2009-2010 in Communities Associated with Jewish Communities in New York."

Similar presentations

Endemic or Outbreak? Differentiating recent transmission of an historic tuberculosis strain in New York City IUATLD-NAR 16 th Annual Meeting February 23-25,

Endemic or Outbreak? Differentiating recent transmission of an historic tuberculosis strain in New York City IUATLD-NAR 16 th Annual Meeting February 23-25,
Screening of Human and Animal Sera from Egypt and Hong Kong Perera et al. Euro Surveill. 2013;18(36):pii=20574 Sampled 1343 Human, 625 animals.

Screening of Human and Animal Sera from Egypt and Hong Kong Perera et al. Euro Surveill. 2013;18(36):pii=20574 Sampled 1343 Human, 625 animals.
IPV IPV Rapidly produces high level of protective antibodies No risk of vaccine associated illness No interference from other enteroviruses. I.P.V. produces.

IPV IPV Rapidly produces high level of protective antibodies No risk of vaccine associated illness No interference from other enteroviruses. I.P.V. produces.
Mumps Outbreak in the Midwest: Implications for College Health Sonja Hutchins, MD, DrPH, FACPM National Center for Immunizations and Respiratory Diseases.

Mumps Outbreak in the Midwest: Implications for College Health Sonja Hutchins, MD, DrPH, FACPM National Center for Immunizations and Respiratory Diseases.
What is one of the most contagious diseases? Measles 2015 Dr. Michael Levy.

What is one of the most contagious diseases? Measles 2015 Dr. Michael Levy.
Lisa Grohskopf, MD, MPH Medical Officer Influenza Division Centers for Disease Control and Prevention U.S. Influenza Surveillance National Center for Immunization.

Lisa Grohskopf, MD, MPH Medical Officer Influenza Division Centers for Disease Control and Prevention U.S. Influenza Surveillance National Center for Immunization.
MUMPS 2006 OUTBREAK.

MUMPS 2006 OUTBREAK.
Hepatitis web study H EPATITIS W EB S TUDY Hepatitis A: Epidemiology Presentation Prepared by: David Spach, MD and Nina Kim, MD Last Updated: May 31, 2011.

Hepatitis web study H EPATITIS W EB S TUDY Hepatitis A: Epidemiology Presentation Prepared by: David Spach, MD and Nina Kim, MD Last Updated: May 31, 2011.
U.S. Surveillance Update Anthony Fiore, MD, MPH CAPT, USPHS Influenza Division National Center for Immunizations and Respiratory Disease Centers for Disease.

U.S. Surveillance Update Anthony Fiore, MD, MPH CAPT, USPHS Influenza Division National Center for Immunizations and Respiratory Disease Centers for Disease.
Hepatitis B: Epidemiology

Hepatitis B: Epidemiology
Varicella Zoster Virus Herpesvirus (DNA) Primary infection results in varicella (chickenpox) Recurrent infection results in herpes zoster (shingles) Short.

Varicella Zoster Virus Herpesvirus (DNA) Primary infection results in varicella (chickenpox) Recurrent infection results in herpes zoster (shingles) Short.
Measles and Measles Vaccine Epidemiology and Prevention of Vaccine- Preventable Diseases National Center for Immunization and Respiratory Diseases Centers.

Measles and Measles Vaccine Epidemiology and Prevention of Vaccine- Preventable Diseases National Center for Immunization and Respiratory Diseases Centers.
MEASLES VACCINATION 2015 Update Susan Reeser RN, BSN (406) 444-1805.

MEASLES VACCINATION 2015 Update Susan Reeser RN, BSN (406)
Infectious Disease Surveillance Section

Infectious Disease Surveillance Section
Learning from the 2009 H1N1 Pandemic Response 1 Daniel S. Miller MD, MPH Director, International Influenza Unit Office of the Secretary Office of Global.

Learning from the 2009 H1N1 Pandemic Response 1 Daniel S. Miller MD, MPH Director, International Influenza Unit Office of the Secretary Office of Global.
Severe Acute Respiratory Syndrome (SARS) and Preparedness for Biological Emergencies 27 April 2004 Jeffrey S. Duchin, M.D. Chief, Communicable Disease.

Severe Acute Respiratory Syndrome (SARS) and Preparedness for Biological Emergencies 27 April 2004 Jeffrey S. Duchin, M.D. Chief, Communicable Disease.
Mumps October 20 2014 Craig Roberts PA-C, MS University of Wisconsin-Madison Robert Palinkas MD University of Illinois at Urbana-Champaign Susan Even MD.

Mumps October Craig Roberts PA-C, MS University of Wisconsin-Madison Robert Palinkas MD University of Illinois at Urbana-Champaign Susan Even MD.
Thomas Clark, MD, MPH Centers for Disease Control and Prevention Immunization Program Managers Meeting November 16, 2010 Pertussis Epidemiology in the.

Thomas Clark, MD, MPH Centers for Disease Control and Prevention Immunization Program Managers Meeting November 16, 2010 Pertussis Epidemiology in the.
Severe Acute Respiratory Syndrome (SARS) and Preparedness for Biological Emergencies 27 April 2004 Jeffrey S. Duchin, M.D. Chief, Communicable Disease.

Severe Acute Respiratory Syndrome (SARS) and Preparedness for Biological Emergencies 27 April 2004 Jeffrey S. Duchin, M.D. Chief, Communicable Disease.
Measles Outbreak in Skopje, Republic of Macedonia, 2014 Erjona Shakjiri 1, D. Kochinski 1, Sh. Memeti 1, B. Aleksoski 1, K. Stavridis 1, V. Mikic 1, G.

Measles Outbreak in Skopje, Republic of Macedonia, 2014 Erjona Shakjiri 1, D. Kochinski 1, Sh. Memeti 1, B. Aleksoski 1, K. Stavridis 1, V. Mikic 1, G.

Similar presentations

Ads by Google