1. The stress response neuropeptide CRF increases amyloid ‐ β production by regulating γ ‐ secretase activity by Hyo ‐ Jin Park, Yong Ran, Joo In Jung, Oliver Holmes, Ashleigh R Price, Lisa Smithson, Carolina Ceballos ‐ Diaz, Chul Han, Michael S Wolfe, Yehia Daaka, Andrey E Ryabinin, Seong ‐ Hun Kim, Richard L Hauger, Todd E Golde, and Kevin M Felsenstein EMBO J. Volume 34(12):1674-1686 June 12, 2015 ©2015 by European Molecular Biology Organization

2. Acute restraint stress and CRF increased endogenous Aβ in C57BL/6J mice forebrains Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization

3. CRF treatment induces the internalization of CRFR1 and γ ‐ secretase Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization

4. The C ‐ terminal domain of CRFR1 mediates the effect of CRF on Aβ levels Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization

5. CRF increases γ ‐ secretase activity in vitro Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization

6. CRFR antagonists do not block CRF ‐ and stress ‐ induced Aβ increases and alter γ ‐ secretase processivity Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization

7. Models for the role of CRF and CRFR antagonists in the localization and activation of γ ‐ secretase and Aβ production in Alzheimer's disease Hyo ‐ Jin Park et al. EMBO J. 2015;34:1674-1686 ©2015 by European Molecular Biology Organization