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GS Case M/53 S10-13057 Small intestine, segmentectomy.

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Presentation on theme: "GS Case M/53 S10-13057 Small intestine, segmentectomy."— Presentation transcript:

1 GS Case M/53 S10-13057 Small intestine, segmentectomy

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13 CK 7 CK 20

14 MUC 1 MUC 2 MUC 6 MUC 5A

15 Diagnosis Small intestine, ileum, segmentectomy: Adenocarcinoma, metastatic Lymph node, mesenteric, segmentectomy: Adenocarcinoma, metastatic (19/27) Appendix, incidental appendectomy: No specific change

16 Diagnosis Correlated with immunohistochemical stain, this case is probably metastasis from pancreas, bile duct, appendix, or colon.

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18 CK 7CK20 Organ ++ Pancreas (65%), Bile duct (65%), Gastric (1/3) +- Lung, Breast, Endometrium, Ovary, Thyroid -+ Large bowel (95%), Gastric (1/3) -- Liver, Kidney, Adrenal present case : CK7 (+), CK20 (+, focal)

19 Small bowel adenocarcinoma 54 cases CK7 in 32%, CK20 in 57% CK7-, CK20+ in 39% CK7+, CK20+ in 19% CK7+, CK20- in 13% CK7-, CK20- in 28% ASCO: GI cancer symposium, 2009 Immunophenotype and molecular characterization of small bowel adenocarcinoma. present case : CK7 (+), CK20 (+, focal)

20 Present case: -, +, -, +


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