1. Date of download: 7/8/2016 Copyright © The American College of Cardiology. All rights reserved. From: Implantable Cardioverter-Defibrillators at End of Battery Life: Opportunities for Risk (Re)-Stratification in ICD Recipients J Am Coll Cardiol. 2016;67(4):435-444. doi:10.1016/j.jacc.2015.11.033 Incidence of ICD Shocks Following Generator Exchange Stratified by Presence of Shocks During First Battery Life Cumulative rate of ICD shocks for detection rates >200 beats/min (bpm) following generator exchange, stratified by uneventful first battery life (group A) versus presence of ICD shocks during first battery life (group B). Cumulative rate and number at risk are specified beneath each time point (21). ICD = implantable cardioverter-defibrillator. Figure Legend:

2. Date of download: 7/8/2016 Copyright © The American College of Cardiology. All rights reserved. From: Implantable Cardioverter-Defibrillators at End of Battery Life: Opportunities for Risk (Re)-Stratification in ICD Recipients J Am Coll Cardiol. 2016;67(4):435-444. doi:10.1016/j.jacc.2015.11.033 Changing Ratio of Sudden Deaths to All-Cause Mortality With Advancing Age Annual rate of sudden death and all-cause death stratified by age in 6,252 patients. Although the rates of both sudden and all-cause mortality increase with age, the rate of increase in all-cause mortality is greater, resulting in a lower proportion of sudden deaths. Figure Legend:

3. Date of download: 7/8/2016 Copyright © The American College of Cardiology. All rights reserved. From: Implantable Cardioverter-Defibrillators at End of Battery Life: Opportunities for Risk (Re)-Stratification in ICD Recipients J Am Coll Cardiol. 2016;67(4):435-444. doi:10.1016/j.jacc.2015.11.033 Paradigm for Weighing the Changes in Risk-Benefit Ratio Between the Time of Initial Implantable Cardioverter-Defibrillator Implant and Generator Exchange Whereas clinical trial data exist to support decision making at the time of initial ICD implant, a lack of high-quality clinical evidence results in much greater uncertainty at the time of generator exchange. Figure Legend: