1. OCULAR MANIFESTATIONS OF SARCOIDOSIS
Dr.ADNAN MATHEEN PG
Dept of OPHTHALMOLOGY

2. SARCOIDOSIS can involve ANY PART of the EYE and may be the MAJOR Manifestation of the Disease, Even Leading to Severe Impairment.
OCULAR INVOLVEMENT– 30%
Most commonly seen in BLACK PEOPLE

3. SYMPTOMS BLURRED VISION PHOTOPHOBIA FLOATERS REDNESS PAIN DRY EYES
LACRIMAL GLAND ENLARGEMENT

4. SIGNS CONJUNCTIVAL NODULES IRIS NODULES ANTERIOR UVEITIS
POSTERIOR SYNECHIAE
PERIPHELBITIS
CYSTOID MACULAR EDEMA

5. CONJUNCTIVAL NODULES

6. IRIS NODULES

8. POSTERIOR SYNECHIAE

9. KERATIC PRECIPITATES
‘MUTTON FAT’ because they are Large and Greasy

11. FUNDUS Posterior segment lesions (20%) Patchy Venous Sheathing
Cellular infiltrate around Vessels
CHORIORETINAL GRANULOMAS
Vasculitis including Occlusive causing:-
Neovascularisation
Infiltrate in Vitreous (Vitritis) including Cell Clumps (Snowballs)

12. PUNCHED OUT

13. CANDLE WAX DRIPPING

14. Sheathing of the Retinal Veins
Fluorescein Angiography showing LEAKAGE and Staining at Sites of Sheathing

15. Granuloma in Fundus
OPTIC NERVE HEAD GRANULOMA
Normal Optic Nerve Head

16. INVESTIGATIONS
BIOPSIES OF
CONJUNCTIVA
LACRIMAL GLAND

17. TREATMENT CYCLOPLEGICS Tropicamide Cyclopentolate Homatropine 2%
TOPICAL STEROIDS
ORAL STEROIDS
CYTOTOXIC DRUGS

18. MIKULICZ SYNDROME ENLARGEMENT OF LACRIMAL GLAND PAROTID GLAND
SALIVARY GLAND
DRY EYES

19. POINTS TO REMEMBER IRIS NODULES PAN UVEITIS POSTERIOR SYNECHIAE
MUTTON FAT KP’s
CANDLE WAX DRIPPINGS
STEROIDS

20. THANK YOU