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NOTES: 7.2 – CELL STRUCTURES & FUNCTIONS
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Comparing the cell to a factory:
● each cell part (“organelle”) can be compared to a specialized machine in a factory; ● each part performs a specific “job” or function towards the functioning of the cell as a whole…
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Cell Organization: ● each eukaryotic cell can be divided into 2 major parts: 1) Cytoplasm 2) Nucleus
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CYTOPLASM: ● CYTOPLASM: the portion of the cell outside the nucleus; mostly water; all other organelles suspended in cytoplasm
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NUCLEUS: ● NUCLEUS: contains nearly all of the cell’s DNA (the coded instructions for making all of the cell’s proteins); ● considered the “control center” of the cell; ● nucleus is surrounded by a nuclear envelope
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NUCLEAR ENVELOPE ● double membrane which encloses the nucleus;
● includes many nuclear pores (holes) which allow material to move in and out of the nucleus
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CHROMATIN ● threadlike complex of DNA bound to proteins; it makes up chromosomes in eukaryotic cells
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CHROMOSOMES ● compacted, coiled up chromatin;
● human cells have 46 chromosomes (23 pairs)
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NUCLEOLUS ● dense, spherical region in the nucleus
-ribosome assembly begins here
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Organelles that Store, Clean Up, and Support:
● vacuoles & vesicles ● lysosomes ● cytoskeleton
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VACUOLE: ● used for storage (of water, salts, proteins, carbs);
● in animal cells, vacuoles are smaller than in plant cells
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PLANT VACUOLES… ● may contain soluble pigments in some cells (red and blue pigments in flowers);
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PLANT VACUOLES… ● help protect from predators by storing waste products that may also be poisonous compounds ● contractile vacuole: specialized vacuole that pumps excess water out of cell.
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VESICLES: ● VESICLES: small, membrane-enclosed structures that store and move materials between cell organelles, or to and from cell surface
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LYSOSOMES: ● the cell’s “clean-up crew”!
● contain digestive enzymes that break down macromolecules into smaller subunits; ● recycle the cell’s own organic material; ● can destroy cells by breaking open all at once and digesting the cell from within
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CYTOSKELETON: ● CYTOSKELETON: provides shape & internal organization; also involved in transport of materials within the cell, as well as whole-cell movement ● includes protein filaments: -microfilaments -microtubules
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Cytoskeleton
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MICROTUBULES & MICROFILAMENTS
● make up the cytoskeleton ● structural support to cell; maintain shape ● involved in cell movement
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Microfilaments: ● threadlike structures; ● made up of protein: ACTIN
● stabilize cell shape ● microfilament assembly & disassembly allow amoebas & other cells to “crawl” along surfaces Yellow: nucleus Green: microfilaments throughout cytoplasm
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Microtubules: ● thin, hollow cylinders made of protein: TUBULIN
● maintain cell shape; ● can serve as “tracks” to guide organelle movement; ● involved in separation of chromosomes in cell division; make up SPINDLE FIBERS / CENTRIOLES (in animal cells)
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Microtubules (cont.)… ● responsible for movement of flagella & cilia
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FLAGELLA and CILIA: ● FLAGELLA: longer usually single extensions; used to propel a cell ● CILIA: shorter and more numerous than flagella; wavelike motion used to sweep extracellular material over/away from cell
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Organelles that Build, Modify, and Transport Proteins:
● ribosomes ● endoplasmic reticulum ● Golgi Apparatus
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RIBOSOMES: ● site of protein synthesis
-small particles of RNA & protein -follow coded instructions from DNA -made in the nucleolus -cells especially active in protein synthesis often contain large #s of ribosomes -may be free (in cytoplasm) or attached to the ER
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ENDOPLASMIC RETICULUM (ER):
● extensive network of internal membranes ● used to transport and/or modify proteins; ● can be ROUGH (ribosomes) or SMOOTH (no ribosomes)
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Rough ER: ● rough appearance due to ribosomes on outer surface;
● newly made proteins leave the ribosomes and are “dropped off” into the rough ER; ● modifies and transports proteins;
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Smooth ER: ● synthesizes lipids, phospholipids, steroids
● detoxifies drugs and poisons
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GOLGI APPARATUS: ● stacked, flattened membranes
● finishes, sorts, packages and ships many cell products (a.k.a. the “post office” of the cell)
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Organelles that Capture and Release Energy:
● chloroplasts ● mitochondria
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CHLOROPLASTS: (“the organelles that feed the world”)
● contain chlorophyll; ● site of photosynthesis (convert light energy into “food”, or chemical energy)
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MITOCHONDRIA: ● sites of cellular respiration
● convert the chemical energy stored in food into usable energy packets for the cell ● the # in cells varies and is related to the cell’s metabolic activity (i.e. if a cell uses more energy, it will have more mitochondria!)
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Cellular Boundaries: ● cell wall ● cell membrane
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Cellular Boundaries: ● CELL WALL:
- semi-rigid structure outside of cell membrane of PLANT CELLS & most prokaryotes; - in plants, consists of CELLULOSE fibers; provides support, limits cell’s volume, and protects against fungi and/or microorganism infection; most cell walls are porous enough to allow water, oxygen, carbon dioxide, etc. to pass through.
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CELL WALL:
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CELL MEMBRANE:
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What must a membrane do? ● let some things leave / enter cell
● keep stuff inside or outside of cell ● be flexible as cell changes shape
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● cell membranes form a LIPID BILAYER that is flexible & can regulate what enters & exits the cell;
● The cell membrane is composed of molecules called PHOSPHOLIPIDS.
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PHOSPHOLIPIDS: -one end is strongly nonpolar (hydrophobic); -one end is extremely polar (hydrophilic)
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● the nonpolar lipid “tails” are repelled by polar water molecules; the polar “heads” of the molecules form hydrogen bonds with water molecules.
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● So, every phospholipid molecule orients so that its polar “head” faces water and its nonpolar “tails” face away... two layers are formed with the tails facing each other...the result is called a LIPID BILAYER.
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Lipid bilayer membranes are:
● PERMEABLE to: lipids nonpolar molecules: O2, CO2 small polar molecules: H2O ● IMPERMEABLE to: ions (Na+, K+, Cl-) large polar molecules: sugars, proteins
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3 Main Types of Cell Membrane PROTEINS…
1) Channels 2) Receptor proteins 3) Cell surface markers
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1. CHANNELS: ● a channel will transport only certain kinds of molecules...which gives the cell membrane its selectively permeable nature
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2. RECEPTOR PROTEINS: ● collect & transmit information from the cell’s environment
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3. CELL SURFACE MARKERS: ● identify your body‘s cells as belonging to you (useful in cell-cell recognition)
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