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Inflammation of both conjunctiva and cornea Red eye, watery Pain on looking at bright Oedema of.

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Presentation on theme: "Inflammation of both conjunctiva and cornea Red eye, watery Pain on looking at bright Oedema of."— Presentation transcript:

1 Keratoconjunctivitis @ Inflammation of both conjunctiva and cornea Symptoms: @ Red eye, watery discharge @ Pain on looking at bright light. @ Oedema of conjunctiva and eyelids @ Subconjunctival haemorrhage

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3 Infectious causes of conjunctivitis: @ Bacteria: # S. aureus # H. influenzae # Str. pneumoniae # Chlamydia trachomatis # N. gonorrhoeae # Ps. aeruginosa. @ Fungi: # Candida

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5 @ Viruses: # Adenoviruses # Herpes simplex virus # Varicella-zoster virus # Enteroviruses, e.g. Coxsackie A24 # Measles. @ Parasites: # Acanthamoeba # Onchocerca volvulus

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7 Diagnosis of Viral Keratoconjunctivitis: @ Collect swabs in viral transport medium @ Tissue culture up to 3 weeks @ Electron microscopy of stool to detect enteric adenoviruses @ Detection of adenovirus antigens by immunofluorescence @ Serology: A rising titre of antibodies is detected in paired sera.

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9 Investigation of Nosocomial Eye Infection @ Culture eye swabs and type all isolates @ Note the collecion dates of eye swabs @ Determine the community-acquired infections (patients attending hospital for the first time) @ Determine the nosocomial infection (patients are reattenders)

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11 Herpes simplex Eye Infections: @ Primary conjunctivitis (self-inoculation) @ Acute conjunctivitis and keratitis @ Corneal ulcers @ Chronic keratitis, ulceration, scarring

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