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Wadley (2014): Effects of exercise on redox protein expression Figure 1 -SO 3 -SO 2 -SOH -SH H2O2H2O2 TRX (-SH)TRX (S-S) Catalytic Cysteine SRX (S-SH)

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Presentation on theme: "Wadley (2014): Effects of exercise on redox protein expression Figure 1 -SO 3 -SO 2 -SOH -SH H2O2H2O2 TRX (-SH)TRX (S-S) Catalytic Cysteine SRX (S-SH)"— Presentation transcript:

1 Wadley (2014): Effects of exercise on redox protein expression Figure 1 -SO 3 -SO 2 -SOH -SH H2O2H2O2 TRX (-SH)TRX (S-S) Catalytic Cysteine SRX (S-SH) SRX (S-S) Reducing Partners Oligomerisation Over-oxidation Monomer TRX-R NADP NADPH Inflammation Stress Signal Proteasome Response PRDX Activity Chaperone Activity

2 Wadley (2014): Effects of exercise on redox protein expression Figure 2 A B * Moderate High LV-HIIT Baseline Exercise Post+30 Β-actin TRX Β-actin TRX Β-actin TRX

3 Wadley (2014): Effects of exercise on redox protein expression Figure 3 A B A * Moderate High LV-HIIT Baseline Exercise Post+30 Β-actin PRDX Β-actin PRDX Β-actin PRDX

4 Wadley (2014): Effects of exercise on redox protein expression Figure 4 ** #

5 Wadley (2014): Effects of exercise on redox protein expression Figure 5 * * *

6 High Intensity (80% VO 2 max) W 30 min Rest 20 min Overnight fast 30 min Rest W 30 min Rest 27 min Overnight fast 30 min Moderate Intensity (60% VO 2 max) Rest W 30 min Rest Overnight fast 30 min Rest 19 min LV-HIIT (90% VO 2 max) Wadley (2014): Effects of exercise on redox protein expression Supplementary Figure 1

7 MODHIGHLV-HIIT BaseExercisePost+30BaseExercisePost+30BaseExercisePost+30 Blood Volume (%) 10094.2 ± 4.7*** 99.9 ± 5.0 $$$ 10092.3 ± 2.9 *** 100.7 ± 4.5 $$$ 10091.8 ± 4.2*** 99.3 ± 4.2 $$$ Plasma Volume (%) 57.6± 2.7 55.8 ± 12.7** 57.5 ± 3.8 $$ 56.4 ± 3.7 48.2 ± 3.5** 56.9 ± 3.8 $$ 57.7 ± 2.3 49.3 ± 4.2** 56.7 ± 4.4 $$ Wadley (2014): Effects of exercise on redox protein expression Supplementary Table 1


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