1. Date of download: 7/9/2016 Copyright © The American College of Cardiology. All rights reserved. From: Pulmonary Vein Total Occlusion Following Catheter Ablation for Atrial Fibrillation: Clinical Implications After Long-Term Follow-Up J Am Coll Cardiol. 2006;48(12):2493-2499. doi:10.1016/j.jacc.2006.08.038 Variation of symptoms with lung perfusion. Scatter diagram showing the relation between the symptoms and the degree of perfusion of the affected lung indicating a negative correlation. As shown in the figure, all patients with grade 3 symptoms had a relative perfusion <25%. Figure Legend:

2. Date of download: 7/9/2016 Copyright © The American College of Cardiology. All rights reserved. From: Pulmonary Vein Total Occlusion Following Catheter Ablation for Atrial Fibrillation: Clinical Implications After Long-Term Follow-Up J Am Coll Cardiol. 2006;48(12):2493-2499. doi:10.1016/j.jacc.2006.08.038 Correlation between lung perfusion and cumulative stenosis index (CSI). Scatter diagram showing the negative correlation between the relative lung perfusion and the CSI. Patients are labeled by their symptom grade. All patients having severe symptoms (grade 3) had a CSI ≥75% and a relative perfusion of 25% (located in the upper left quadrant). S. grade = symptom grade (0 = asymptomatic; 1 = mild symptoms; 2 = moderate; 3 = severe). Figure Legend:

3. Date of download: 7/9/2016 Copyright © The American College of Cardiology. All rights reserved. From: Pulmonary Vein Total Occlusion Following Catheter Ablation for Atrial Fibrillation: Clinical Implications After Long-Term Follow-Up J Am Coll Cardiol. 2006;48(12):2493-2499. doi:10.1016/j.jacc.2006.08.038 Correlation between timing of intervention and perfusion improvement. The scatter diagram shows the relation between the time from pulmonary vein occlusion diagnosis to the time of intervention and the improvement of the affected lung perfusion. Cases are labeled according to the degree of improvement of the cumulative stenosis index as detected by computed tomography scan. As shown, despite adequate restoration of vascular patency, later interventions were not associated with a significant improvement of perfusion. CT imp. = improvement of cumulative stenosis index by computed tomography. Figure Legend: