1. Aerobic Respiration Part 1: Overview & Krebs Cycle

2. Objectives Relate aerobic respiration to the structure of a mitochondrion Relate aerobic respiration to the structure of a mitochondrion Summarize the events of the Krebs cycle Summarize the events of the Krebs cycle Calculate the efficiency of the Krebs cycle Calculate the efficiency of the Krebs cycle Contrast the roles of glycolysis and aerobic respiration in cellular respiration Contrast the roles of glycolysis and aerobic respiration in cellular respiration

3. Overview of Aerobic Respiration Two major stages: Two major stages: Krebs cycle Krebs cycle Krebs cycle finishes the _______ of glucose and makes ________ & some ATP Krebs cycle finishes the _______ of glucose and makes ________ & some ATP Electron transport chain Electron transport chain Electron transport chain produces the majority of the _____ in the process of _______________ Electron transport chain produces the majority of the _____ in the process of _______________

4. Location of Aerobic Respiration Prokaryotes Prokaryotes Krebs cycle & electron transport chain take place in the ____________ Eukaryotes Eukaryotes Krebs cycle takes place in the ____________ Electron transport chain takes place __________ Electron transport chain takes place __________ Matrix: is the space inside the _________________ Cristae: is the _____ of the inner membrane

5. Intermediate Step Between Glycolysis & the Krebs cycle there is an intermediate step that occurs as ____________diffuses into the mitochondria from the _______________ Between Glycolysis & the Krebs cycle there is an intermediate step that occurs as ____________diffuses into the mitochondria from the _______________

6. KREBS CYCLE Is a ________ pathway that breaks down __________, producing CO 2, hydrogen atoms, and ATP Is a ________ pathway that breaks down __________, producing CO 2, hydrogen atoms, and ATP This cycle was discovered by Hans Krebs in 1937. This cycle was discovered by Hans Krebs in 1937. He was awarded a Nobel Prize in 1953. He was awarded a Nobel Prize in 1953. Also known as the __________ cycle Also known as the __________ cycle It has 5 major steps that occur in the ________________________ It has 5 major steps that occur in the ________________________

7. KREBS CYCLE 1.Acetyl CoA (2C) combines with ________________(4C) producing citric acid (6C) and regenerating ___________ 2._______releases CO 2 and a hydrogen atom to form a 5C compound. NAD + is _______ into NADH + H + 3.5C compound releases CO 2, a H + atom, and forms a 4C compound. NAD + is reduced into NADH + H + again. ATP is also made

8. KREBS CYCLE 4.4C compound releases H + to form another 4C compound and FAD is reduced to _____________ 5.The second 4C compound releases a H + atom to regenerate _______________ NAD + is reduced into NADH + H + again Cycle runs _______ to use all the pyruvic acid made in glycolysis

10. Energy Accounting of Krebs Made: Made: The energy molecules from glycolysis and Krebs drive the next step of aerobic respiration The energy molecules from glycolysis and Krebs drive the next step of aerobic respiration