2. Klaus F. Rabe MD, PhD and the Challenges of Chronic Respiratory Disease...

5. 500 400 300 200 100 0 Rate per 100 000 population 1970 1978 1986 1994 2002 Heart Disease Cancer Year of Death Stroke Jemal A. et al. JAMA 2005; 294: 1255-1259. -52% -63% -2.7%

6. Year of Death 75 1970 1978 19861994 2002 50 25 0 Accidents Chronic Obstructive Pulmonary Disease Diabetes Jemal A. et al. JAMA 2008; 294: 1255-1259. -41% +100% +3%

7. Global Alliance against Chronic Respiratory Diseases www.who.int/respiratory/gard DiseasePrevalence Asthma300 million COPD210 million Allergic rhinitis400 million Sleep apnea>100 million Others>50 million Everyone in the world is exposed to CRD risk factors often common with other NCDs Co-morbidities - paramount importance - often common with other NCDs Global challenges

18. POPULATION IMBALANCES IN 2025

19. SEVERE INCOME DISPARITY IS SEEN TO BE THE NUMBER 1 GLOBAL RISK OVER NEXT 10 YEARS

20. GLOBAL SNAPSHOT OF INEQUALITY

21. OECD AREA For every 0.05 increase in Gini coefficient of income inequality, mortality increased 7.8%, with an estimated 1.5 million excess deaths each year in 30 countries in the OECD.

22. LESS WEALTH MEANS LESS HEALTH Source: Wilkinson and Pickett, The Spirit Level (2009)

24. HEALTH INEQUALITY IN THE UK

25. FP7 Health research i.e. € 6 billion (11%) FP7 Respiratory research (4.3%) i.e. € 261 million COPD & asthma research (0.5%) i.e. € 31 million FP7 TOTAL: € 54 BILLION FP7 HEALTH RESEARCH:€ 6 BILLION (11%) EU 7 th Framework Programme (FP7)

26. –Focus on 4 major NCDs: cardiovascular, respiratory, cancer & diabetes –Implementing the “Political Declaration” adopted at the UN HLM on NCDs (19-20 Sep) “We now have a unique opportunity to take action on chronic respiratory disease and we need to raise maximum awareness. I hope that ERS members from across the world will join me in pressing the UN agencies, WHO and governments to ensure they meet the ambitious commitments made in the Political Declaration to prevent and control NCDs.” – Y. Sibille