1. Overview of Diagnosed and Undiagnosed Diabetes in the United States—2007 1. American Diabetes Association. Diabetes Care. 2008;31:1-20. 2. American Diabetes Association. National Diabetes Fact Sheet, 2005. http://www.diabetes.org/diabetes-statistics.jsp. Accessed February 8, 2008.  Incidence: ~ 1 million new cases diagnosed yearly 1  Vast majority (>90%) of cases are type 2 diabetes 2 People Without Diabetes: 288 million 1 People With Diabetes: 24.1 million (8% of the population) 1 Diagnosed: 17.5 million 1 Undiagnosed: 6.6 million 1

2. Estimated Costs of Diabetes in the United States—2007 Direct: $116 Billion Institutional Care Outpatient Care Outpatient Medications Indirect: $58 Billion* $65.8B $22.7B $27.7B Per capita medical expenditures: $11,744 with diabetes, $2,935 without Adapted from American Diabetes Association. Diabetes Care. 2008:31:1-20. Total Expenditures: $174 Billion $26.9B $2.6B $20B $7.9B Mortality Lost Workdays Permanent Disability Reduced Work Performance *Includes $0.8 billion in reduced productivity days for those not in labor force.

3. Impact of Diabetes in the United States—2007 Adapted from American Diabetes Association. Diabetes Care. 2008;31:1-20. Diabetes 77,000 CVD 123,000 Cerebrovascular Conditions 59,000 Renal Conditions 25,000 Total: 284,000 deaths Number of Deaths Diabetes $9.5 billion CVD $11.4 billion Cerebrovascular Conditions $3.8 billion Renal Conditions $2.1 billion Total: $26.9 billion Lost Productivity ($)

4. Estimated Annual Costs of Diabetes in the United States—1992-2020 Adapted from American Diabetes Association. Diabetes Care. 2008;31:1-20. Billions ($) 19922002 2007 2010*2020* *2003 estimate. 156 192 174 132 92 0 50 100 150 200