1. Acute appendicitis The department of faculty and hospital surgery of the medical faculty of the Tashkent medical academy

2. HISTORY Leonardo da Vinchi and Andreasa Vezaliya described appendix at first in 16 v. But in that time it described like inflammation of the muscles in iliac region («psoitis») and treated with drugs. →→→→→→

3. First appendectomy was performed in London in 1735 year by English surgeon Claudius Amyand. The patient was 11 year boy.

4. In 1838 year doctor Iogan Albert gave name to diseases as «tiflitis» (paratiflitis, peritiflitis). In 1886 year R.H.Fitz gave name to disease as «acute appendicitis» first and suggested that one of the best methods of treatment is operation.

5. Clinic manifestation was described at first in 1889 year by A. McBurney and one of the symptoms of appendicitis named by his name. approach that was used during the appendectomy named after Mak Burney, but at first this access was used by McArtur.

6. The first appendectomy under the control of the laparoscopy was performed by De Kok in 1977 year with the minilaparotomy to delete the appendix. At first the LAE was performed by K. Semm in 1982 year at the patient with the pathology of the apurtenances, moreover the changes of the appendix weren’t acute

7. In Russia in 1988 year K.P. Dombrovskiy at first operated patient with appendicular abssessus. In 1921 year 60 –year American surgeon Even Keyn in own body performed operation appendectomy.

8. Epidemiology Frequency - to 200-300 people one with the acute appendicitis. In UIC during the year performed about 1 mln. operation with acute inflammation of the appendix. In our country during the year more 500 thousand patients are hospitalized and about 89% patients are operated. Postoperative death – 0,2-0,3%

9. Acute appendicitis – non specific inflammation of the appendix

10. Projection of the appendix onto the anterior abdominal wall

11. normal medial retrocaecal Localization of the appendix comparatively to the caecum

12. In the pelvis Subhepatical localization Variants of the localization of the appendix in the abdominal cavity

13. Blood circulation of the appendix Arterial circulation Aorta – а.mesenterica superior – a.ileocolica – a.appendicularis Venous system v.appendicularis – v.ileocolica – v. mesenterica superior – v.portae

14. Spreading of the acute appendicitis among the acute surgical diseases Acute appendicitis Acute cholecystitis Ulcer disease of the duodenum

15. Factors of the frequency of the postoperative complications and death at the acute appendicitis №AuthorsYearFrequency of the complications Factor of death 1.Savchuk B.D.1998 9,8%0,31% 2.Savelev V.S.1999 8,7%0,24% 3.Gostishev V.К.2001 7,6%0,21% 4.Dronov А.F.2002 7,9%0,26% 5.Shurkalin B.К.2003 8,6%0,28% 6.Kriger А.G.2005 7,6%0,22% 7.Goodwin C.S2004 7,3%0,19% 8.Bohnen J.M.2005 8,2%0,23%

16. Frequency of the acute appendicitis depend on the age Acute appendicitis is the most spreaded surgical disease. fem mal Frequency of the acute appendicitis depend on the gender

17. Etiology and pathogenesis of the acute appendicitis Breach of the nervous regulation of the appendix Breach of the blood circulation of the appendix ACUTE APPENDICITIS Sensibilisation of the organism (allergy, hookworms invasion) Reflector way (diseases of the stomach, liver, intestine) Direct irritation of nerves (alien object in the appendix, excrement stone, bends) Spasm of the muscles and vessels of the appendix Hypostasis of the wall of the appendix Closing of the mouth of the appendix

18. Classification of the acute appendicitis Simple appendicitis Destructive appendicitis: flegmonous, gangrenous, perforative Complicated appendicitis: appendicular infiltrate, appendicular abscess, peritonitis, pilephlebitis and other.

19. Normal appendix

20. Acute simple appendicitis

21. Acute destructive appendicitis Empiema of the appendix Gangrenous perforative appendicitis

22. Complaints the most frequent 1 – pain in the right iliac area 1. Beginning of the pain in the epygastria with the transition to the right iliac area (Cocher-Volkovich symptome) 2. Constant (seldom fight), 3. Low intensivity (blunt, nagging) 4. Without the irradiation 2 – sickness, retching (once or twice) 3 – weakness, loss of appetite

23. Constipation – at the peritonitis Tenesms – at the pelvic localization Diarrhea – at the medial localization Disuria – at the retrocaecal localization Dryness in the mouth, ballooned abdomen – at the peritonitis Complaints depending on the localization of the appendix and stage of the process

24. Local symptoms of the acute appendicitis Voscresenskiy («shirt») – identification of the most painful zones at the sliding of the hand above the shirt Rovsing – increasing of pain in the right iliac area at pushing to the left Razdolskiy– pain at the percussion in the right iliac area Sitkovskiy – tumbling from the back to the left side inducts pain in the right iliac area Bartom’e-Mikhelson– palpation of the right iliac area at the state of the patient on the left side inducts pain Cocher-Volkovich – transition of the pain from the epigastria to the right iliac area

25. General symptoms of the acute appendicitis Dryness and coverness of the tongue Tachycardia Subfebril temperature Rising of the SES Leucocytosis with the movement of the formula to the left

26. Particularities of the clinic currency of the acute appendicitis At children. Fast development of the destructive changes (perforation), short omentum – spreading of the infection, prevalence of the general symptoms over the local: enxiety, breach of sleeping, rising temperature to 38,5-39С, increasing pain in the abdomen without defined localization, frequent sickness, retching, diarrhea. At elders. Low significance of the main symptoms: pain, pain at the palpation, effort of the muscles, the temperature is normal or increased a little, the leucocytes of blood are without changes, aptitude to the development of throbs, early development of the destructive changes, more frequent development of the complications. At pregnant. Denominated pain appears later, in not typical place, but above and to the right from the uterus, seldom in the lumbar area, effort is less denominated Indicate the symptoms of the appendicitis is complicative or impossible frequently under the mask of pyelonephritis of pregnants.

27. Differential diagnostic of the acute appendicitis Diseases of the organs of the abdominal cavity Diseases of the organs of the chest Diseases of the organs of the extraperitoneal space Infectional diseases Diseases of the vessels Gynecological diseases Diseases of skin Neurological diseases

28. Ultrasound research Presence of the free liquid

29. Laparoscopy Special methods of diagnostic

30. Diagnostic laparoscopy More reliable method, that allows directly find out the source of the peritonitis, presence and character of the excaudate.

31. Laparoscopic signs of the inflammated appendix (by Criger А.G., 2000) Not changed appendix free droops on the instrument At the inflammation the appendix doesn’t droop because of the hypostasis, periodically slides

32. Incision of Dyakonov-Volkovich

33. Stages of the access Section of the aponeurosis Separation of the muscles Opening of the peritoneum

34. Stages of the operation Extracting of the dome of the caecum Removing of the appendix Bandaging of the mesentery of the appendix

35. Stages of the operation Putting of the pouch stitch Appendectomy Submersion of the loop of the appendix

36. Stages of the retrograd appendectomy

38. Character and frquency of the postoperative complications Wound complications– 80% Intraperitoneal – 6% Bronchopulmonary – 4% Cardio-vascular – 3% Others – 7%

39. The reasons of the not satisfactory results of the traditional appendectomy Defeat of the different cutaneus and muscle’s nerves Defeat of the vessels, inducting the development of the haemotomas, and wound complications Defeat of the muscular-aponeurotic tissues promotes the development of the postoperative hernias Manipulations, performing in the abdominal cavity indicate the soldering process in the abdominal cavity High per cent of the diagnostic mistakes, that confirmed by the high weight of the “cataral” appendicitis

40. History of the endoscopic surgery of the acute appendicitis The first appendectomy under the control of the laparoscopy was performed by De Kok in 1977 year with the minilaparoto my to delete the appendix At first the LAE was performed by K. Semm in 1982 year at the patient with the pathology of the apurtenances, moreover the changes of the appendix weren’t acute In 1987 year Schrieber J.H. has carried out the laparoscopic appendectomy because of acute appendicitis

41. Morphologic characteristic of the acute appendicitis in different groups Cataral FlegmonousGangrenous Control groupMain group

42. Variants of performing of the laparoscopic appendectomy With using of the endostapler Endo- Gia-30 With using of the endoloop of Roeder With using of clipses

43. Laparoscopic appendectomy with the help of endoligature

44. Laparoscopic appendectomy with the help of clipping

45. Laparoscopic appendectomy with the help of endoscopic suturing instruments

46. Comparative estimation of the clinic picture in different groups Dynamic of changing of the painful syndrome Dynamic of changing of the moving activity

47. Comparative estimation of the postoperative complications in different groups Early complications (to 15 days) Lately complications (more than 3 months) Wound complications Abscess of the Douglas’s space Breach of the sensitivity Acute intestinal obstruction Breach of the sensitivity Laparoscopic appendectomy Traditional appendectomy

48. Analysis of the reasons of the conversions at performing of the laparoscopic appendectomy 1. retrocaecal, retroperitoneal localization of the appendix; 2. duration of the disease to the moment of the admition more than 48 hours; 3. technic impossibility of deleting of the appendix by the laparoscopic access during 1 hour from the moment of the beginning of the operation.

49. Group of the patients, at which it is better to perform the laparoscopic appendectomy 1. the patients, at which it is impossible to exclude acute appendicitis during the dynamic observation. Performing of the diagnostic laparoscopy allows to confirm the diagnosis, at the case of finding out the acute appendicitis - LAE. 2. the women of the reproductive age. Performing of the endoscopic research allows to carry out the differential diagnostic between the acute appendicitis and acute gynecological pathology. Besides, the reduction of the weight of the ungrounded appendectomies warns the development of soldering process and as a result – secondary sterility. 3. patients with the acompanying diabetes, obesity and other predisposing factors of the development of the wound complications. Using of the LAE at these patients reduces the risk of development of the wound complications.

50. Contraindications to the laparoscopic appendectomy 1. duration of the disease more than 48 hours. 2. diffuse peritonitis. At this case it is impossible ti carry out the sanation of the abdominal cavity. 3. general contraindications to the laparoscopy – pulmonary-cardiac insufficiency, big term of the pregnancy, acute infarct of myocardium, additional diseases, not allows to increase the intraabdominal pressure, presence of the significant soldering process in the abdominal cavity

51. Nowadays there is used transluminal appendectomy. Here may be 2 access: 1.Transgastral. 2.Transvaginal.