1. Meiosis

2. Two Types of Diploid Cells In Sexual Organisms Body Cells Diploid Divide by mitosis to make exact copies In every tissue except reproductive tissue “Germinating” (reproductive) cells Diploid (Most) Divide by meiosis to make gametes (sex cells) (sperm & ova) In testes & ovaries SomaticGERM

3. Mitosis vs. Meiosis Asexual ReproductionSexual Reproduction Body cells (somatic) Sex cells (gamete) DNA replicates once # cell divisions: 1 # cell divisions: 2 2 identical daughter cells 4 different daughter cells Makes Diploids (2N) Makes Haploids (1N)

4. What is an “n”? Haploid (n) is the number of chromosomes in a gamete. Diploid (2n) – number of chromosomes in a somatic cell. You have one copy from the mother, and one copy from the Father.

5. Meiosis is part of SEXUAL Reproduction (requiring 2 parents)

6. In Meiosis: ONE diploid, germ cell divides to become FOUR (4) daughter cells (*circle*) … diploid / haploid (*circle*) … somatic / gamete

7. Splits homologous pairs of chromosomes Splits sister chromatids apart Meiosis IMeiosis II In order to go from diploid to haploid, Meiosis Involves Two Divisions

8. Time To Name The Phases PROPHASE I METAPHASE I ANAPHASE I TELOPHASE I PROPHASE II METAPHASE II ANAPHASE II TELOPHASE II

9. Make 2 Tables PROPHASE IMETAPHASE IANAPHASE I TELOPHASE I & CYTOKINESIS WHAT IT LOOKS LIKE WHAT’S GOING ON TABLE I

10. Make 2 Tables PROPHASE IIMETAPHASE IIANAPHASE II TELOPHASE II & CYTOKINESIS WHAT IT LOOKS LIKE WHAT’S GOING ON TABLE II

11. PROPHASE I Nuclear envelope disintegrates Centrioles migrate, produce spindle fibers Homologous chromosomes pair up Homologous pairs CROSS OVER!

12. PROPHASE I CROSSING OVER Occurs when homologous chromosomes exchange segments of genes

13. METAPHASE I Homologous pairs of chromosomes line up along metaphase plate

14. ANAPHASE I Homologous pairs pulled apart to opposite poles

15. TELOPHASE I & CYTOKINESIS Chromosomes (no longer homologous pairs!) prepare for meiosis II Cytoplasm begins to split into first 2 (of 4) daughter cells

16. TELOPHASE I & CYTOKINESIS NOTE: At the end of meiosis I, daughter cells are already Haploid! (because homologous pairs were separated)

17. 2 haploid daughter cells then go through MEIOSIS II In Meiosis II, 2 haploid cells will separate sister chromatids to make 4 gametes!

18. PROPHASE II Centrioles migrate, produce spindle fibers Just like in mitosis!

19. METAPHASE II Chromosomes line up along metaphase plate Just like in mitosis!

20. ANAPHASE II Sister chromatids pulled apart to opposite poles Just like in mitosis!

21. TELOPHASE II & CYTOKINESIS Nuclear envelopes reform around 4 daughter cells Cytoplasm splits to separate the 4 daughter cells Each of the 4 daughter cells is a new gamete with genetic information different from either parent!

22. Is This Meiosis I or Meiosis II? Why?

23. Is This Meiosis I or Meiosis II? Why?

24. Meiosis I Meiosis II Check – Point: At what point do the cells become haploid?

25. Mitosis v. Meiosis

26. But what happens to the other 3 eggs? The largest ovum absorbs the others! 200 to 400 million sperm per ejaculate! Only one wins per cycle, usually

27. Finally, Fertilization Male and female gametes unite Fusion of two haploid nuclei produces diploid nucleus Egg + Sperm = Zygote (new life in one diploid cell)

28. Meiosis and Sexual Reproduction Guarantee Variation and Diversity!

29. 1.Independent Assortment Homologous Chromosomes separate randomly 2.Crossing Over Homologous pairs exchange gene segments 3.Random Fertilization Which sperm meets which egg? (game of chance) In Three Ways