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January 26, 2004BME 272/2731 Investigation of Bubble Formation in Tuohy-Borst Adaptors Department of Biomedical Engineering Melanie Bernard, Isaac Clements,

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Presentation on theme: "January 26, 2004BME 272/2731 Investigation of Bubble Formation in Tuohy-Borst Adaptors Department of Biomedical Engineering Melanie Bernard, Isaac Clements,"— Presentation transcript:

1 January 26, 2004BME 272/2731 Investigation of Bubble Formation in Tuohy-Borst Adaptors Department of Biomedical Engineering Melanie Bernard, Isaac Clements, & Jason Hirshburg Advisor: Ted Larson III, M.D.

2 January 26, 2004BME 272/2732 Introduction Dr. Larson has 15 years of experience in interventional neuroradiology Catheters uses: –Angiography –Embolization of arteriovenous fistulas –Aneurysms –Preoperative embolization of neck and intracranial tumors www.angiodynamics.com

3 January 26, 2004BME 272/2733 Problem Bubbles are seen within the Tuohy-Borst Adaptor –Can get stuck in small arteries in brain, inhibiting the supply of blood and oxygen –Causes stroke and death –Once present, bubbles are difficult to remove because they stick to inner surface of system http://www.cookurological.com/products/ureteroscopy

4 January 26, 2004BME 272/2734 What is causing bubble formation? Our task is to discover the cause and correct it Observations: Bubbles are seen… –Stuck to inner surface of adaptor –At the edge of the Y-junction –Even before microcatheter is inserted –When catheter flow is reversed and blood hits the edge of the Y-junction and interfaces with the saline (or contrasting agent)

5 January 26, 2004BME 272/2735 Previous Work Observed device in a medical procedure on 11/18/03 Literature Search Innovation WorkBench

6 January 26, 2004BME 272/2736 Current Work : Setup Obtained tubes and adaptors to recreate Dr. Larson’s setup

7 January 26, 2004BME 272/2737 Current Work : Procedure Adjusted pressures and valves to simulate surgery conditions

8 January 26, 2004BME 272/2738 Current Work : Results Observed lots and lots of bubbles already present throughout the system!

9 January 26, 2004BME 272/2739 Future Work Redesign experiments based on previous results –Simulate actual pressures (~100 mmHg for blood pressure) and temperatures (body and room) –Use actual blood Software models of fluid flow, using Computational Fluid Dynamics (CFD) software. Examine the effects of the differences between the two adaptor types www.ent.ohiou.edu/ ~mehta/cfd.htm

10 January 26, 2004BME 272/27310 For more information… Visit our website at http://vubme.vuse.vanderbilt.edu/srdesign/2003/group17/

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