1. Formation of human hepatocytes by human hematopoietic stem cells in sheep by Graça Almeida-Porada, Christopher D. Porada, Jason Chamberlain, Ali Torabi, and Esmail D. Zanjani Blood Volume 104(8):2582-2590 October 15, 2004 ©2004 by American Society of Hematology

2. Adult human HSCs generate significant numbers of hepatocytes in a noninjury fetal model. Graça Almeida-Porada et al. Blood 2004;104:2582-2590 ©2004 by American Society of Hematology

3. Human hepatocytes generated in vivo from the human hematopoietic stem cells are functional. Graça Almeida-Porada et al. Blood 2004;104:2582-2590 ©2004 by American Society of Hematology

4. In situ hybridization shows that cells within the vessel walls and biliary ducts are of human origin. Graça Almeida-Porada et al. Blood 2004;104:2582-2590 ©2004 by American Society of Hematology

5. Different phenotypes of HSC have different characteristics regarding hepatocyte production. Graça Almeida-Porada et al. Blood 2004;104:2582-2590 ©2004 by American Society of Hematology

6. Human hepatocyte generation in the fetal sheep model is not caused by cell fusion. Graça Almeida-Porada et al. Blood 2004;104:2582-2590 ©2004 by American Society of Hematology