1. National Institutes of Health U.S. Department of Health and Human Services William A. Suk, Ph.D., M.P.H. Director, Superfund Research Program Chief, Hazardous Substances Research Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Water Research Innovation from the NIEHS Superfund Research Program – An Integrated Approach for Sustainable Solutions www.niehs.nih.gov/srp 1

2. National Institutes of Health U.S. Department of Health and Human Services NIEHS Superfund Research Program (SRP) Health: Toxicology and Epidemiology Engineering: Monitoring and Remediation Clean Drinking Water -Health studies related to drinking water contaminants -Methods to reduce the amount and toxicity of hazardous substances in water -Detection and assessment of hazardous substances Clean Drinking Water -Health studies related to drinking water contaminants -Methods to reduce the amount and toxicity of hazardous substances in water -Detection and assessment of hazardous substances Risk Levels & Dose Response Risk Levels & Dose Response Technologies Innovation Copy of SARA Legislation Hazardous Substances: -Currently on Superfund Sites -Emerging Contaminants of Concern Hazardous Substances: -Currently on Superfund Sites -Emerging Contaminants of Concern Basic research grant program Superfund Amendment Reauthorization Act (SARA), 1986 2

3. National Institutes of Health U.S. Department of Health and Human Services SRP Model: Integrated Approach to Solve Complex Problems Translate research to policy makers to improve drinking water quality Engage with communities: What is user-friendly? Health: Toxicology and Epidemiology Clean Drinking Water Access Clean Drinking Water Access What is “Clean”? Are we achieving “Clean”? How to achieve “Clean”? What is “Clean”? Are we achieving “Clean”? How to achieve “Clean”? 3 Engineering: Monitoring and Remediation

4. National Institutes of Health U.S. Department of Health and Human Services Advances in Water Research: Health 4 Investment in epidemiology and toxicology research delivers science-based policy for safe drinking water First step: Identifying exposures that may cause harm Detecting contaminants in drinking water Linking metals and other contaminants to preterm birth, cancer neurodevelopmental outcomes, decreased lung function, etc. Subsequent step: Determining methods to prevent or reduce harmful exposures Improving cleanup of aquifers at hazardous waste sites Increasing the efficiency to immobilize or remove contaminants

5. National Institutes of Health U.S. Department of Health and Human Services Integration of Health Advances Sets Goals for Technology Innovation Technology specifications: Which contaminants to look for? What concentrations? What level of contaminant removal is adequate? Are byproducts of remediation less toxic? Long-term: Exposure Prevention Remediation of pollution at the sources in groundwater and surface water Protecting water ecosystem services (natural resources) Toxicology and Epidemiology Monitoring and Remediation What is “Clean”? Are we achieving “Clean”? How to achieve “Clean”? What is “Clean”? Are we achieving “Clean”? How to achieve “Clean”? 5

6. National Institutes of Health U.S. Department of Health and Human Services Technology Innovation: New Solutions Improved Water Monitoring –Real-time and rapid monitoring of water –Multi-analyte samplers –Passive sampling devices Innovative, Sustainable Remediation –Biological-based (biofiltration, bioremediation) –In situ (in place) remediation –Membrane technologies (i.e., nano- enhanced) Membrane Technology 6 Biologically-based technology

7. National Institutes of Health U.S. Department of Health and Human Services 7 Contaminants Studied in Water Monitoring and Remediation Projects (Funded by SRP in FY 2011-2015) 7

8. National Institutes of Health U.S. Department of Health and Human Services Opportunities and Challenges Technology Transfer – How to reach end-users? –To reach regulatory agencies: Health investigators take initiative to serve on panels - IARC, IRIS, CMERC –To reach the water industry: Recent engagement between integrated water systems/groups (i.e., EPA Water Clusters) and technology developers –To reach communities: Researchers utilize best practices for community engagement Other Opportunities: –Data integration and sharing NIH and Federal initiatives to share data Transparency of results can build confidence in new technologies Area of interest to the SRP 8

9. National Institutes of Health U.S. Department of Health and Human Services More Webinars to Come! Water Remediation Technologies Water detection technologies Exposures and Health Outcomes Community Engagement bit.ly/waterSRP 9

10. National Institutes of Health U.S. Department of Health and Human Services Thank You! More Information: SRP Website: www.niehs.nih.gov/srpwww.niehs.nih.gov/srp Small Business Progress in Research Webinars: bit.ly/SBIRwaterSRPbit.ly/SBIRwaterSRP Contact us: Bill Suk, Ph.D., M.P.H. (919) 541-0797 suk@niehs.nih.gov Heather Henry, Ph.D. 919-541-5330 henryh@niehs.nih.gov Stay Tuned for More Webinars! SRP Water Innovation - An Integrated Approach to Sustainable Solutions bit.ly/waterSRP Stay Tuned for More Webinars! SRP Water Innovation - An Integrated Approach to Sustainable Solutions bit.ly/waterSRP 10