Presentation is loading. Please wait.

Presentation is loading. Please wait.

Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009.

Published byEileen Theresa Heath Modified over 8 years ago

Similar presentations

Presentation on theme: "Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009."— Presentation transcript:

1 Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009 Chemical structures of thyroxine, triiodothyronine, and amiodarone. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2 Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009 Changes in thyroid hormone physiology and thyroid function test results in euthyroid patients who received amiodarone.43334The following changes in thyroid function test results occur: 1) increase in serum levels of thyroxine (T ) and reverse triiodothyronine [rT ], 2) initial increase followed by normalization of serum levels of thyroid-stimulating hormone [TSH], and 3) decrease in serum levels of triiodothyronine (T ). Asterisks indicate steps in thyroid hormone dynamics inhibited by amiodarone. Daggers indicate physiologic feedback inhibition. Bold arrow indicates that most feedback inhibition of TSH production is mediated by T rather than T. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3 Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009 Suggested algorithm for evaluation and management of thyroid dysfunction in patients treated with amiodarone.43*Test should be done to serve as a reference for comparison with future test results. † Goal is to increase serum levels of thyroxine (T ) to high normal or slightly above normal (normalization of levels of thyroid-stimulating hormone [TSH] should not be attempted). ‡ Combination of thionamides (methimazole, 40 mg/d, or propylthiouracil, 400 to 800 mg/d) with potassium perchlorate (800 to 1000 mg/d for 15 to 45 days) or prednisone (0.5 to 1.25 mg/kg of body weight per day for 40 days) is beneficial; β-blockers may be added. AIH = amiodarone-induced hypothyroidism; AIT = amiodarone-induced thyrotoxicosis; T = triiodothyronine. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

Download ppt "Date of download: 9/17/2016 From: Effects of Amiodarone on Thyroid Function Ann Intern Med. 1997;126(1):63-73. doi:10.7326/0003-4819-126-1-199701010-00009."

Similar presentations

Date of download: 5/31/2016 From: Polymorphonuclear Leukocytes in Non-Insulin-dependent Diabetes Mellitus: Abnormalities in Metabolism and Function Ann.

Date of download: 5/31/2016 From: Polymorphonuclear Leukocytes in Non-Insulin-dependent Diabetes Mellitus: Abnormalities in Metabolism and Function Ann.
Date of download: 6/2/2016 From: Antibiotic Self-stewardship: Trainee-Led Structured Antibiotic Time-outs to Improve Antimicrobial Use Ann Intern Med.

Date of download: 6/2/2016 From: Antibiotic Self-stewardship: Trainee-Led Structured Antibiotic Time-outs to Improve Antimicrobial Use Ann Intern Med.
Date of download: 6/2/2016 From: Internet-Based Self-management Plus Education Compared With Usual Care in Asthma: A Randomized Trial Ann Intern Med. 2009;151(2):110-120.

Date of download: 6/2/2016 From: Internet-Based Self-management Plus Education Compared With Usual Care in Asthma: A Randomized Trial Ann Intern Med. 2009;151(2):
Date of download: 6/3/2016 From: Mortality Rates in Elderly Patients Who Take Different Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial.

Date of download: 6/3/2016 From: Mortality Rates in Elderly Patients Who Take Different Angiotensin-Converting Enzyme Inhibitors after Acute Myocardial.
Date of download: 6/3/2016 From: Chest Pain Relief by Nitroglycerin Does Not Predict Active Coronary Artery Disease Ann Intern Med. 2003;139(12):979-986.

Date of download: 6/3/2016 From: Chest Pain Relief by Nitroglycerin Does Not Predict Active Coronary Artery Disease Ann Intern Med. 2003;139(12):
Date of download: 6/3/2016 From: Sex, Age, and Birth Cohort Effects in Colorectal Neoplasms: A Cohort Analysis Ann Intern Med. 2010;152(11):697-703. doi:10.7326/0003-4819-152-11-201006010-00002.

Date of download: 6/3/2016 From: Sex, Age, and Birth Cohort Effects in Colorectal Neoplasms: A Cohort Analysis Ann Intern Med. 2010;152(11): doi: /
Date of download: 6/3/2016 From: Elevated Plasma Homocysteine Level Is an Independent Predictor of Coronary Heart Disease Events in Patients with Type.

Date of download: 6/3/2016 From: Elevated Plasma Homocysteine Level Is an Independent Predictor of Coronary Heart Disease Events in Patients with Type.
Date of download: 6/3/2016 From: Increased Incidence of Aortic Aneurysm and Dissection in Giant Cell (Temporal) Arteritis: A Population- Based Study Ann.

Date of download: 6/3/2016 From: Increased Incidence of Aortic Aneurysm and Dissection in Giant Cell (Temporal) Arteritis: A Population- Based Study Ann.
Date of download: 6/6/2016 From: Comparative Effectiveness of Pain Management Interventions for Hip Fracture: A Systematic Review Ann Intern Med. 2011;155(4):234-245.

Date of download: 6/6/2016 From: Comparative Effectiveness of Pain Management Interventions for Hip Fracture: A Systematic Review Ann Intern Med. 2011;155(4):
Date of download: 6/17/2016 From: Treatment of Rheumatoid Arthritis with Gammalinolenic Acid Ann Intern Med. 1993;119(9):867-873. doi:10.7326/0003-4819-119-9-199311010-00001.

Date of download: 6/17/2016 From: Treatment of Rheumatoid Arthritis with Gammalinolenic Acid Ann Intern Med. 1993;119(9): doi: /
Date of download: 6/21/2016 From: The Epidemiology of Prescriptions Abandoned at the Pharmacy Ann Intern Med. 2010;153(10):633-640. doi:10.7326/0003-4819-153-10-201011160-00005.

Date of download: 6/21/2016 From: The Epidemiology of Prescriptions Abandoned at the Pharmacy Ann Intern Med. 2010;153(10): doi: /
Date of download: 6/22/2016 From: The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature Ann Intern Med. 1995;123(7):518-527.

Date of download: 6/22/2016 From: The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature Ann Intern Med. 1995;123(7):
Date of download: 6/23/2016 From: Meta-Analysis: Acupuncture for Low Back Pain Ann Intern Med. 2005;142(8):651-663. doi:10.7326/0003-4819-142-8-200504190-00014.

Date of download: 6/23/2016 From: Meta-Analysis: Acupuncture for Low Back Pain Ann Intern Med. 2005;142(8): doi: /
Date of download: 6/24/2016 From: Effectiveness of Manual Physical Therapy and Exercise in Osteoarthritis of the Knee: A Randomized, Controlled Trial Ann.

Date of download: 6/24/2016 From: Effectiveness of Manual Physical Therapy and Exercise in Osteoarthritis of the Knee: A Randomized, Controlled Trial Ann.
Date of download: 6/24/2016 From: Sodium–Glucose Cotransporter 2 Inhibitors for Type 2 Diabetes: A Systematic Review and Meta-analysis Ann Intern Med.

Date of download: 6/24/2016 From: Sodium–Glucose Cotransporter 2 Inhibitors for Type 2 Diabetes: A Systematic Review and Meta-analysis Ann Intern Med.
Date of download: 6/25/2016 Copyright © 2016 American Medical Association. All rights reserved. From: The Colorado Thyroid Disease Prevalence Study Arch.

Date of download: 6/25/2016 Copyright © 2016 American Medical Association. All rights reserved. From: The Colorado Thyroid Disease Prevalence Study Arch.
Date of download: 6/25/2016 From: Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic.

Date of download: 6/25/2016 From: Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic.
Date of download: 6/28/2016 From: Meta-Analysis: Low-Dose Dopamine Increases Urine Output but Does Not Prevent Renal Dysfunction or Death Ann Intern Med.

Date of download: 6/28/2016 From: Meta-Analysis: Low-Dose Dopamine Increases Urine Output but Does Not Prevent Renal Dysfunction or Death Ann Intern Med.
Date of download: 6/28/2016 From: Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase–Associated.

Date of download: 6/28/2016 From: Sensitivity and Specificity of a Single Emergency Department Measurement of Urinary Neutrophil Gelatinase–Associated.
Date of download: 6/29/2016 From: Predicting Future Functional Status for Seriously Ill Hospitalized Adults: The SUPPORT Prognostic Model Ann Intern Med.

Date of download: 6/29/2016 From: Predicting Future Functional Status for Seriously Ill Hospitalized Adults: The SUPPORT Prognostic Model Ann Intern Med.

Similar presentations

Ads by Google