1. Hemophilia By: Rebecca Peterson, Owen Comer, Quaevon Anderson, and Grace Hodges

2. Basic Information Grace Hemophilia A Classic hemophilia Factor VIII deficiency Hemophilia B Christmas disease Factor IX deficiency The name hemophilia was chosen because “hemo” means blood and “philia” means like.

3. Discovery of hemophilia Grace Hemophilia was discovered in Plymouth, New Hampshire, in 1720. It was not named until 1828, though. The men who discovered and named hemophilia are Friedrich Hopff and Dr. John Conrad Otto. The reason this disease was discovered is because it was traced back through three generations of women in Plymouth. It was also mentioned in 2nd century AD in a collection of Jewish Rabbinical writings.

4. How is Hemophilia cured? Quaevon Hemophilia can’t be cured, but it can be treated and controlled. Self treatment: Tranexamic acid by mouth (Lysteda or by injection). and also common-IV fluids Hemophilia is treated by injecting the missing factor replace therapy.

5. Living with hemophilia Quaevon If you or your child has hemophilia you can take steps to prevent bleeding problems. improvements in treatment a child who has hemophilia today is likely to live a normal lifestyle.

7. Symptoms and Effects Owen Symptoms: Large and deep bruises Joint pain and swollen joints Unexpected bleeding Internal bleeding Effects: When injured, you can bleed for a prolonged amount of time. Joints don’t function as well as they should. Loss of joint space

8. Diagnosis of Individual Owen Doctors use clotting factor tests. These are required to diagnose a bleeding disorder, and show the type of the hemophilia and the severity. They also use screening tests, which are blood tests that show if the blood is clotting properly. ⅓ of babies who get hemophilia have no family history of the disease Usually, people have the disease at the start of their life, but in some rare cases, someone can develop it later in life.

9. Prognosis of Individual Quaevon people who get care are provided with treatment. A person without proper treatment for their hemophilia may not live to see adulthood. If the patient is treated, they usually live about 10 years less than the average male without hemophilia. People with hemophilia bleed more than people without hemophilia. If the bleeding is severe enough, the patient may require medical attention.

10. Current research Rebecca Currently Wake Forest school of medicine is trying to find out how to use gene therapy to cure people with hemophilia. They think that they might be able to place a stem cell from an adult into the patient's body with the ability to make more of the clotting factor VIII.

11. Treatments and medications Rebecca There is currently no cure to hemophilia but there are some medications that you can take to help such as lysteda. You can also have an injections of plasma to help with your clotting. You can also possibly have gene therapy done to help with the preventing of hemophilia, but it hasn’t been tested much so the results are dangerous.

13. A Famous person with hemophilia Grace Abraham Lincoln, America’s 16 th president had hemophilia. The genetic disease did not stop him from ending slavery and improving the country. He was still a good president, and did not die because of his hemophilia (he was assassinated). Lincoln also had a family, and led our country for a little over one term (killed in office in term two). Abraham Lincoln also had other illnesses, such as Multiple Endocrine Neoplasia 2B. In conclusion, this case of hemophilia did not greatly affect Lincoln.

14. Bibliography Grace Www.google.com/search?q=Hemophilia. Www.google.com/search?q=Hemophilia (n.d.): n. pag. Hemophilia. Google. Web. Donald, David H., Deborah Hayden, Samuel A. Schreinen, John G. Sotos, and Ronald C. White, “Medical and Mental Health of Abraham Lincoln”- Wikipedia, the free encyclopedia. n.p. n.d. Web. 14 Mar. 2016 Chien-Kang Ding, Guest Lecture”-Duke University: Genetics outreach- organization, Durant Road Middle School, 23 Feb. 2016 "Diagnosis." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 13 Sept. 2011. Web. 04 Apr. 2016. "Hemophilia." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 16 Mar. 2016. Web. 04 Apr. 2016. Koyfman, Andrew, and Rob Hunter. "Stop the Bleeding: Can Gene Therapy Finally Cure Hemophilia? | Xconomy." Xconomy RSS. N.p., 22 Mar. 2015. Web. 05 Apr. 2016.