1. Examination 4 questions from 6 2 will be compulsory (ie. A big word meaning YOU HAVE TO DO THEM) 2 hours to complete test (portion approx 30mins per question (attempt to write 4 solid answers/ not 3 good answers and one lousy one) Remember that unless you include a bit of evidence of additional reading (ie material not taught in class the max you will get is 8/10) Essay style/ can use diagrams Write as LEGIBLY as is conceivably possible

2. Topic outline Molecular Analysis of Development -Descriptive embryology -Genetics and molecular biology Techniques for the study of Development Gastrulation and early development (1) Anterior/Posterior, Dorsal ventral axis formation (2) Major Model Organisms- Mouse, Chick, Xenopus, C.elegans, Drosophila,Zebrafish Programs and Regulatory Elements in DNA (3) Transcription Receptors, Ligands (4) Signalling Networks Cell Division/ Lineage Generation Cell Differentiation (5) 3 D Patterning (6) - limb development

3. Strategies for revision A) learn each topic (eg Transcription, gastrulation, Receptors and ligands, Signalling networks etc. BUT! Remember that these are not discrete entities- think about links between different parts of the course

4. Q. Discuss the signalling pathways that regulate eve transcription in Drosophila mesoderm development

5. Q. Discuss the signalling pathways that regulate eve transcription in drosophila mesoderm development A) signalling pathways (pathways regulating the transcripton (DPP/ Wingless) B) eve transcription (not all of the enhancers directing stripe formation- only the mesoderm enhancer) C) dros mesoderm dev (NOT stripe pattern)

6. Think also about examples from different model systems Eg if the topic is gastrulation We have discussed aspects of it in chick/mammals/ drosophila

7. Think in broad terms about topics that span the course Eg. axis specification (Dros/ vertebrate limb) A-P D-V L-R Morphogens Drosophila/ Vertebrate Neural Tube) Similarities between pathways (DPP/ BMP)

8. In your answers think about the possible inclusion of reference to specific experimental technology where appropriate