1. ANTIDERM de-reddening and soothing

2. ANTIDERM OLEA EUROPEA (OLIVE FRUIT OIL) LIPOREDUXANTIDERMCOMPOSITION BALSAM COPAIBA (COPAIFERA OFFICINALIS)

3. VERY WELL KNOWN COMPONENTS Antimicrobial Terpenoids from the Oleoresin of the Peruvian Medicinal Plant Copaifera paupera. Planta Medica 2002, 68: 808-812 Investigation on the Wound Healing Activity of Oleoresin from Copaifera langsdorffi in Rats. Phytotherapy Research 16, 737-739 (2002) Anti-inflammatory activity of oleoresin from brazilian Copaifera. Journal of Ethnopharmacology, 22 (1988) 101-109 Gastroprotective effect of Copaifera langsdorffii oleoresin on experimental gastriculcer models in rats. Journal of Ethnopharmacology, 62 (1998) 73-78 Extracts of Bolivian plants, Copaifera reticulate and Heisteria pallida Inhibit in vitro Free Radical-mediated DNA Damage. Phytoterapy research, Vol. 11, 460-462 (1997) Protective effect of Copaifera langsdorffii oleoresin against acetic acid-induced colitis in rats. Journal of Ethnopharmacology, 93 (2004) 51-56 ) 51-56 LIPOREDUXANTIDERM

4. In Vivo Test LIPOREDUX ANTIDERM

5. Without protection With ANTIDERM 2 4 6 8 10 Reddening score ► Time ► 0’ 5’ 15’ 30’ SOOTHING EFFECT L (artificially irritated forearm skin) 20 people (age between 18 and 70 years old) Cream with 5% of Antiderm LIPOREDUXANTIDERM

6. 35 37 39 Mositurization ► Time ► 0’ 15’ 30’ MOISTURIZATION AFTER USE L (Corneometer) 20 people (age between 18 and 70 years old) Cream with 5% of Antiderm LIPOREDUXANTIDERM

7. 34 36 38 Time ► 0 15 days Mositurization ► L MOISTURIZATION AFTER CONTINUOS USE (Corneometer) 20 people (age between 18 and 70 years old) Cream with 5% of Antiderm LIPOREDUXANTIDERM

8. natural antinflammatory emollient ANTIDERM LIPOREDUXANTIDERM

9. IDEAL FOR: Irritated and reddened skin, itchy, sensitive and dry skin Delicate skin (children) Atopic and aspecific dermatitis Damage caused by many factors: excessive solar exposure, nappy dermatitis, frequent contact with aggressive detergents. LIPOREDUXANTIDERM

10. Thank you Via Pastore 1 - 25082 Botticino Sera (Brescia) Italy Tel. +39 0302693532 - Fax. +39 0302193581 www.kalichem.it www.kalichem@kalichem.it