2. Chapter 40 Homeostasis

3. Animal Form and Function  Animals provide examples of biology’s major themes  diversity & unity of life  form & function are interwoven  evolution is the thread that ties it all together  adaptations observed in a comparative study of animals evolved by natural selection The cold-adapted rabbit has short ears and extremities to reduce heat lost, while the heat- adapted jackrabbit has longer ears that act as heat exchangers with ambient air.

4. Big Idea #2 Biological systems utilize free energy and molecular building blocks to grow, to reproduce, and to maintain dynamic homeostasis.

5. Conformers vs. Regulators  2 evolutionary paths for organisms  regulate internal environment  maintain relatively constant internal conditions  conform to external environment  allow internal conditions to fluctuate along with external changes conformer thermoregulation regulator conformer osmoregulation regulator

6. Hierarchy of Structure  cells  tissues  organs  organ systems  tissues = groups of cells with common structure and function  organs = composed of different tissue types  organ systems = organs working towards the same function  tissues = groups of cells with common structure and function  organs = composed of different tissue types  organ systems = organs working towards the same function

7. Organ Systems cells tissues organs organ system organism cells tissues organs organ system organism

8. intracellular waste extracellular waste Animal systems evolved to support multicellular life… O2O2 CHO aa CH CO 2 NH 3 aa O2O2 CH O2O2 aa CO 2 NH 3 O2O2 aa CH aa CHO O2O2 Diffusion too slow!

9. Homeostasis  Keeping the balance  animal body needs to coordinate many systems all at once  temperature  blood sugar levels  energy production  water balance & intracellular waste disposal  nutrients  ion balance  cell growth  maintaining a “steady state” condition

10. Homeostasis  systems work to maintain a balance  integrated open and closed systems  requires monitoring, feedback, and response

11. Feedback Circuits  Negative feedback  stimulus triggers control mechanism counteracting further change  reverse effect  Positive feedback  stimulus triggers control mechanism amplifying effect  much less common  Feed-forward control  changing the set point at which the desired equilibrium should be

12. Negative Feedback high low hormone 1 lowers body condition hormone 2 gland specific body condition raises body condition gland Negative Feedback Model

13. Positive Feedback not that common in living systems not that common in living systems

14. Feedforward Information  using feedback from senses, the driver regulates the speed of a car

15. Q 10  the temperature sensitivity of a reaction or process  = R T /R T-10  most biological Q 10 values are between 2 and 3

16. What -therm are you?  ectotherm  animals whose body temperature are determined by external heat sources  endotherm  regulate body temperature by producing metabolic heat or prevention of heat loss  heterotherm  can behave like either  hibernating mammals

17. BMR (Basal Metabolic Rate)  measured when a resting animal is consuming just enough to carry out its minimal life functions within the thermoneutral zone  when the metabolic rate of endotherms is low and independent of temperature

18. Controlling Body Temperature high low nerve signals sweat nerve signals body temperature (37°C) shiver dilates surface blood vessels constricts surface blood vessels hypothalamus

19. Thermoregulation Vasoconstriction Vasodilation  Vasodilation & vasoconstriction  adjusts blood flow  evaporative cooling

20. Temperature Management Cold blood Capillary bed Veins 5˚C environmental temperature 36˚C core body temperature Artery blood from arteries warms blood in veins Warm blood

21. Osmoregulation Why do all land animals have to conserve water?  always lose water (breathing & waste)  may lose ‘life’ while searching for water  always lose water (breathing & waste)  may lose ‘life’ while searching for water  Water balance  freshwater  hypotonic  water flow into cells & salt loss  saltwater  hypertonic  water loss from cells  land  dry environment  need to conserve water  may need to conserve salt

22. Waste Disposal  What waste products?  what do we digest our food into…  carbohydrates = CHO  lipids = CHO  proteins = CHON  nucleic acids = CHOPN  relatively small amount in cell CO 2 + H 2 O NH 2 into ammonia  CO 2 + H 2 O  CO 2 + H 2 O + N  CO 2 + H 2 O + P + N | ||| H H N C–OH O R H –C– cellular digestion… cellular waste

23.  Ammonia (NH 3 )  very toxic  carcinogenic  very soluble  easily crosses membranes  must dilute it & get rid of it… fast!  How you get rid of nitrogenous wastes depends on:  who you are (evolutionary relationship)  where you live (habitat) Nitrogenous Waste Disposal

24.  Aquatic organisms  can afford to lose water  ammonia  most toxic  Terrestrial  need to conserve water  urea  less toxic  Terrestrial egg layers  need to conserve most water  uric acid  least toxic Nitrogen Waste