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Shimura Supplemental Figure 1

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Presentation on theme: "Shimura Supplemental Figure 1"— Presentation transcript:

1 Shimura Supplemental Figure 1
HepG2 HeLa Cell Number (x105) Day

2 Shimura Supplemental Figure 2
HeLa % of apoptotic cells Dose of X-ray (Gy)

3 Time after irradiation (hour)
Shimura Supplemental Figure 3 A B 10 Gy 12 hours 10 Gy 24 hours 31FR G2-phase (37.02%) G2-phase (68.58%) BrdU G2-phase fraction (%) 31FR-31NR G2-phase (32.09%) G2-phase (75.48%) Time after irradiation (hour) DNA content

4 Shimura Supplemental Figure 4
C HeLa 0FR 31FR 0FR 31FR IR (Gy) Cyclin D1 Cdk4 HE Actin B Cyclin D1 Tumor Volume (mm3) Day

5 Shimura Supplemental Figure 5
Cdk4 CCND1 Cdk2 Level of Expression 0FR 14FR 31FR 45FR 0FR 14FR 31FR 45FR 0FR 14FR 31FR 45FR

6 Shimura Supplemental Figure 6
10-Gy Irradiation 0FR 31FR After CHX (minutes) Cyclin D1 Actin 10-Gy Irradiation Relative cyclin D1 levels Time after CHX (min)

7 Shimura Supplemental Figure 7
HepG2 HeLa 2Gy 0.5Gy 2Gy 0.5Gy Time after IR (hr) P-AKT (Ser473) AKT Actin B HepG2 HeLa 2Gy 0.5Gy 2Gy 0.5Gy Time after IR (hr) P-GSK3b (Ser9) GSK3b Actin

8 Shimura Supplemental Figure 8
HepG2 HeLa 0FR 31FR-31NR 0FR 31FR-31NR KU-55933 P-ATM P-AKT (Ser473) AKT Actin

9 Shimura Supplemental Figure 9
0FR 31FR-31NR HepG2 tail HeLa tail

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