3. A Match!

5. Small Large Genetic distances

6. DNA GPS is online Searching for DNA origin… Latitude = 57.69 Longitude = 2.46 Geographic Population Structure (GPS)

7. 100% (Continent) 83% (Country) 66% (Regional) Sardinian villagers dataset 15 km 100 km Genographic’s global dataset

10. Geographical coordinates, nearest reference populations Genetic data

11. Afshinnekoo et al. 2015. Geospatial resolution of human and bacterial diversity with city-scale metagenomics. Cell Systems

12. All data included (r 2 =0.5) High quality data included (r 2 =0.7) 12 admixture compressed to 4 4 racial groups

13. We developed a pipeline to infer geographical origins and ancestry very accurately from microbiome data. Our tools can handle a large amount of data. We can carry out geographic and spatial analyses regarding human biodiversity in relation to the microbiome.