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Date of download: 9/18/2016 From: Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update Ann Intern Med.

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Presentation on theme: "Date of download: 9/18/2016 From: Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update Ann Intern Med."— Presentation transcript:

1 Date of download: 9/18/2016 From: Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update Ann Intern Med. 2008;149(3):177-184. doi:10.7326/0003-4819-149-3-200808050-00241 Forest plot of studies estimating sensitivity of interferon-γ–release assays in patients with active tuberculosis as a surrogate for latent tuberculous infection.Point estimates for sensitivity and 95% CIs are shown along with pooled estimates. Top. QuantiFERON-TB Gold (16 studies). Middle. QuantiFERON-TB Gold In-Tube (6 studies). Bottom. T-SPOT.TB (13 studies). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2 Date of download: 9/18/2016 From: Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update Ann Intern Med. 2008;149(3):177-184. doi:10.7326/0003-4819-149-3-200808050-00241 Forest plot of studies estimating specificity of interferon-γ–release assays in populations at very low risk for latent tuberculous infection.Point estimates for specificity and 95% CIs are shown along with pooled estimates. Top. QuantiFERON-TB Gold and QuantiFERON-TB Gold In-Tube (braille Calmette–Guérin [BCG] nonvaccinated; 8 studies). Middle. QuantiFERON-TB Gold and QuantiFERON-TB Gold In-Tube (BCG vaccinated; 8 studies). Bottom. T-SPOT.TB (predominantly BCG vaccinated; 6 studies). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3 Date of download: 9/18/2016 From: Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update Ann Intern Med. 2008;149(3):177-184. doi:10.7326/0003-4819-149-3-200808050-00241 Forest plot of studies estimating sensitivity and specificity of the tuberculin skin test.Point estimates for sensitivity and specificity and 95% CIs are shown along with pooled estimates. Top. Sensitivity (20 studies). Middle. Specificity in non–bacille Calmette–Guérin-vaccinated populations (6 studies). Bottom. Specificity in bacille Calmette–Guérin-vaccinated populations (6 studies). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

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