1. E.Q. What are the components of DNA? p26 10/6 Monomer = Nucleotide Polymer = Nucleic acid Phosphate Sugar (deoxyribose) Nitrogenous Base DNA!!

2. THE BIG PICTURE Cells

3. Cell Membrane

4. Molecule Movement

5. Carbs, Lipids, and Proteins Also used as energy from food

6. Nucleus

7. A lesson from Jurassic Park...

9. How many parts to a Nucleic Acid??

10. 1 2 3

11. Phosphate Nitrogenous Base Sugar

13. Half a DNA Nitrogenous Base Phosphate Sugar

14. Full DNA Phosphate Nitrogenous Bases

15. DNA Double Helix Nitrogenous Base (A,T,G or C) “Rungs of ladder” “Legs of ladder” Phosphate & Sugar Backbone

16. For Thursday: A HISTORY OF DNA DNA double helix Discovery of the DNA double helix A.Rosalind Franklin - X-ray photo of DNA. (1952) B.Watson and Crick - described the DNA molecule from Franklin’s X-ray. (1953)

17. Nitrogenous Base

18. Nitrogenous Bases PURINES PURINES Adenine (A) 1.Adenine (A) Guanine (G) 2.Guanine (G) PYRIMIDINES PYRIMIDINES Thymine (T) 3.Thymine (T) Cytosine (C) 4.Cytosine (C) T or C A or G

19. Adenine Thymine Adenine must pair with Thymine GuanineCytosine Guanine must pair with Cytosine about the same Their amounts in a given DNA molecule will be about the same. G C TA The apple grows on the tree! The car goes in the garage!

20. Apples Grow on Trees Adenine to Thymine

21. Cars go in Garages Cytosine to Guanine

22. DNA Double Helix P P P O O O 1 2 3 4 5 5 3 3 5 P P P O O O 1 2 3 4 5 5 3 5 3 G C TA HYDROGEN BONDS

23. The differently shaped bases are bonded together antiparallel to one another (5’  3’)antiparallel DNA ladder will twist into a double helix shape

24. Antiparallel

25. Important to Remember: All living things have DNA! Scientists refer to this as a “common genetic code” The sequence of bases matters! The order determines the organism.

26. Replicating DNA DNA Molecule #1 G T C A C T G T G C T A

27. Replicating DNA DNA Molecule #1 G T C A C T G T G C T A CAGTGACACGATCAGTGACACGAT