1. DNA Investigation: Across the Universe Pennsylvania Homicide Investigators Association April, 2016 State College, PA Mark W Perlin, PhD, MD, PhD Cybergenetics, Pittsburgh, PA Cybergenetics © 2003-2016

2. Deposit DNA

3. Associate DNA Match +10

4. Deposit ‘N Associate Match +10

5. TrueAllele ® Casework ViewStation User Client Database Server Interpret/Match Expansion Visual User Interface VUIer™ Software Parallel Processing Computers

6. Exclusion Mismatch -10

7. Low-level or degraded Match +6

8. Mixture Match +8

9. Inconclusive mixture Crime laboratory DNA report Crime lab user fee: $5,000 Conclusions: Item 1 – Swab of textured areas from a handgun The data indicates that DNA from four (4) or more contributors was obtained from the swab of the handgun. Due to the complexity of the data, no conclusions can be made regarding persons A and B as possible contributors to this mixture.

10. Computer reanalysis Cybergenetics TrueAllele ® report Match statistics provide information 1 2 3 4 Person B included 400,000 Person A excluded Unmix the mixture Contributor

11. Evidence to Evidence Match +8

12. Murder in McKeesport, PA

13. Match +9 Match +16 Mixture matches

14. Mixture mismatches Only Defendant deposited DNA to both items of evidence

15. Crime scene investigation Match +9

16. DNA left at 5 different scenes Food mart gun hat Hardware safe phone Jewelry counter safe Convenience keys tape Market hat 1 hat 2 overalls shirt

17. Serial crime investigation Food mart gun hat Hardware safe phone Jewelry counter safe Convenience keys tape Market hat 1 hat 2 overalls shirt Suspects: S1, S2, S3, S4, S5

18. Pennsylvania v James Yeckel, Jr. Son (suspect) Father (deceased) Mother (deceased) Father Mother Son Match +12

19. TrueAllele in Allegheny County CrimeEvidenceDefendantOutcomeSentence rapeclothingRalph Skundrichguilty75 years murdergun, hatLeland Davisguilty23 years rapeclothingAkaninyene Akanguilty32 years murdershotgun shellsJames Yeckel, Jr.guilty plea25 years murderfingernailAnthony Morganguiltylife weaponsgunThomas Doswellguilty plea1 year bank robberyclothingJesse Lumbergerguilty10 years drugsgunDerek McKissickguilty plea2 1/2 years drugsgunSteve Morganguilty plea2 1/2 years murderdoor, clothingCalvin Kaneguilty plea20 years murdergunJaykwaan Pinckneyguilty plea10 years child rapeclothingDhaque Jonesguilty plea6 years shootinggunAnthony Jeffersonguilty plea4 years weaponsgunDelmingo Williamsguilty plea3 years incest rapeclothingTerry L.guilty40 years bank robberyhatRobert Schatzmanguiltypending weaponsgunRashawn Walkerguilty1.5 years robberyhatLauren Peakguilty plea1 year murdergunChaz Whiteguilty plea4 years 44 cases, 8 trials, 3 DNA exonerations

20. Investigative power CapabilityHuman reviewTrueAllele Data choiceSelection biasUse all data UncertaintyThresholdsStatistics NeutralInclude onlyInclude/Exclude StatisticHow many testsMatch information ObjectiveNoYes ValidatedNo (0)Yes (30) AccurateNoYes Frye challengeNoYes Item-to-itemNoYes Touch DNANoYes Complex mixtures2-3, 50%-100%2-10, 5%-100% Database10%100%

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