2. A Little History…

3. King Henry VIII

4. King Henry VIII Story Born: 28 June 1491, Greenwich Palace Father: King Henry VII Mother: Elizabeth of York Reigned: 1509 - 1547 Died: 28 January 1547

5. King Henry VIII

6. The 6 wives of King Henry VIII

7. 1) Catherine of Aragon (divorced)

8. 2) Anne Boleyn (beheaded)

9. 3) Jane Seymour (died after giving birth)

10. 4) Anne of Cleaves (divorced)

11. 5) Catherine Howard (beheaded)

12. 6) Catherine Parr (survived)

13. Catherine of Aragon - divorced Anne Boleyn - beheaded Jane Seymour - died Anne of Cleaves - divorced Catherine Howard - beheaded Catherine Parr - survived The wives of King Henry VIII

14. Moral: Don’t anger the King.

15. Why was the King angry with his wives?

16. Sex is determined by males!

17. Technically it was his own fault…

18. Write a summary of the King Henry VIII Story. (~3 Sentences)

20. 46 Chromosomes in every body cell

21. 44 Chromosomes are autosomal

22. 2 chromosomes code for sex

23. Male = XY Sex Chromosomes Female = XX

24. Aa fF gene Qq Don’t copy this slide.

25. XXXY marries

26. XXXY X marries

27. XXXY X marries

28. XXXY X XY marries

29. XXXY X XY marries GirlBoy

30. In DNA, what matches with “A”?

31. In DNA, what matches with “G”?

32. 3 billion base pairs in a body cell

33. Allele 1 Allele 2 Chromosome Don’t copy this.

35. Color Blindness is a sex-linked recessive condition Sex-linked means X-linked!

36. Males X N Y = Normal X n Y = affected

37. Females X N X N = Normal X N X n = Carrier X n X n = affected

38. Ishihara Test for Color Blindness

49. Normal color vision should have seen a “5”. Red/green color blindness should have seen a “2”.

52. Hardy-Rand-Rittler Test Try to find a circle, square, star and/or boat in the next couple of pictures.

53. Normal vision should see the yellow and “faint” brown objects. Color Blind people should only see the yellow objects.

58. Hemophilia = recessive and X-linked

59. Males X N Y = Normal X n Y = affected

60. Females X N X N = Normal X N X n = Carrier X n X n = affected

61. X N X n Y

62. X N X n Y XNXN

63. X N X n Y XNXN XnXn

64. X N X n Y XNXN XnXn Y

65. X N X n Y XNXN XnXn Y X N X n X N Y

66. Can a hemophiliac father pass his bad allele to his son? X n Y

67. NO! He passes the bad allele to his daughters! X n Y

68. Y Hemophilia SonDaughter X n