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Copyright © 2016 McGraw-Hill Education. All rights reserved.

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1 Copyright © 2016 McGraw-Hill Education. All rights reserved.
From: Chapter 338. Principles of Endocrinology Harrison's Principles of Internal Medicine, 18e, 2012 Legend: Nuclear receptor signaling. ER, estrogen receptor; AR, androgen receptor; PR, progesterone receptor; GR, glucocorticoid receptor; TR, thyroid hormone receptor; VDR, vitamin D receptor; RAR, retinoic acid receptor; PPAR, peroxisome proliferator activated receptor; SF-1, steroidogenic factor-1; DAX, dosage-sensitive sex-reversal, adrenal hypoplasia congenita, X-chromosome; HNF4α, hepatic nuclear factor 4α. Date of download: 11/12/2016 Copyright © 2016 McGraw-Hill Education. All rights reserved.

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Lecture 06 – Intracellular Signal Receptors Lecture 06 – Intracellular Signal Receptors BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared.

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2 4 6 8 10010 1 RLU x10 4 - NBBS [µM] Fig. 1S human GR  no hormone Glucocorticoid 10 -11 M Fig. 1S NBBS does not effect the transactivation mediated by.

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Date of download: 6/1/2016 From: Syndromes of Glucocorticoid Resistance Ann Intern Med. 1993;119(11):1113-1124. doi:10.7326/0003-4819-119-11-199312010-00009.

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Nuclear Receptor The fourth type of receptors we will consider belong to the nuclear receptor family. By the 1980s, it was clear that receptors for steroid.

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Copyright © 2016 McGraw-Hill Education. All rights reserved.

Copyright © 2016 McGraw-Hill Education. All rights reserved.
Auris O. Huen, PharmD, MD, Ellen J. Kim, MD  Dermatologic Clinics 

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Paralysis of conjugate gaze to the opposite side: Frontal contraversive eye field or projecting fibers Source: Cerebrovascular Diseases, Harrison's Principles.

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(Adapted, with permission, from Fagin JA

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A chamber designed to treat multiple patients

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Copyright © 2015 by the American Osteopathic Association.

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(Reproduced, with permission, from Findling JW

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