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Published byGilbert Williamson Modified over 8 years ago
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Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell–, and not B cell–, dependent antilymphoma immunity by Hong Qin, Soung-chul Cha, Sattva S. Neelapu, Yanyan Lou, Jinsong Wei, Yong- Jun Liu, and Larry W. Kwak Blood Volume 114(19):4142-4149 November 5, 2009 ©2009 by American Society of Hematology
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Administration of myotoxins at vaccination sites significantly enhanced idiotype DNA vaccine- induced tumor protection. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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Prophylactic antitumor effects of additional DNA vaccines were significantly improved by the combined vaccination therapy. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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The combined vaccination therapy elicited memory and therapeutic antitumor immunity. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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Combined cardiotoxin and DNA vaccine elicited potent, T cell–dependent, tumor antigen– specific immunity. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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Anti-idiotype antibody response was not required for the vaccine-induced tumor protection. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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Cardiotoxin administration recruits antigen-presenting cells and converts nonimmunogenic, unfused antigen into a protective vaccine. Hong Qin et al. Blood 2009;114:4142-4149 ©2009 by American Society of Hematology
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