1. BNFO 615 Fall 2016 Usman Roshan NJIT

2. Outline Machine learning for bioinformatics – Basic machine learning algorithms – Applications to bioinformatics Assignments and quizzes – Expect about five through the semester – Carry 50% of total grade Project – Student gives proposal with expected outcome – Final evaluation based on expected outcome

3. Topics Background and Python Basic machine learning algorithms – Linear classification – Support vector machines – Decision trees and random forests – Neural networks Disease risk prediction Phenotype prediction

4. Topics Protein sequence classification Metagenomics – machine learning approaches Protein sequence alignment via machine learning Predicting binding sites in DNA HMMs for gene discovery Deep learning methods in genomics