1. Deficient cortical development in the hydrocephalic Texas (H ‐ Tx) rat: a role for CSF by Farhad Mashayekhi, Clare E. Draper, Carys M. Bannister, Mohsen Pourghasem, P. Jane Owen ‐ Lynch, and Jaleel A. Miyan Brain Volume 125(8):1859-1874 August 1, 2002 ©2002 by Oxford University Press

2. Fig. 1 (A and B) Sagittal sections through the brain of day 21 H ‐ Tx foetuses showing the aqueduct obstruction that occurs in (B) affected H ‐ Tx but not (A) unaffected foetuses after day 18. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

3. Fig. 2 The diagrams show (A) sagittal and (B) coronal views of the foetal rat brain. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

4. Fig. 3 Photomontages of methyl green–pyronin ‐ stained coronal sections across the thickness of the cortical mantle from the brains of gestational day 19 (A–C) and 2 ‐ day ‐ old (D–F) (postnatal) Wistar (A and D), unaffected H ‐ Tx (B and E) and affected H ‐ Tx (C and E) rats. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

5. Fig. 4 The thickness of the (A) cerebral cortex (CC) and (B) germinal epithelium (GE) was measured in comparable coronal sections from Wistar rats (filled diamonds) and unaffected (open squares) and affected (open triangles) H ‐ Tx rats at days 14–24 days after conception. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

6. Fig. 5 Photomontage of BrdU antibody ‐ stained coronal sections through the cerebral cortex of Wistar (A and C), unaffected H ‐ Tx (B and D) and affected H ‐ Tx (E) day 18 foetuses (A and B) and pups 1 day after birth (C–E), whose mothers were injected with BrdU on day 17 (A and B) or day 19 of gestation (C–E). Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

7. Fig. 6 The numbers of BrdU ‐ positive cells in the germinal epithelium (GE), intermediate zone (IZ) and cortical plate (CP) of the cerebral cortical sections were counted. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

8. Fig. 7 The numbers of BrdU ‐ positive cells in the germinal epithelium (GE), intermediate zone (IZ) and cortical plate (CP) were counted in comparable sections of the cerebral cortex from Wistar (black bars), unaffected H ‐ Tx (white bars) and affected H ‐ Tx (hatched bars) rat foetuses and pups on days 20–23 after mating (A–D, respectively) after the pregnant dams had been injected with BrdU on day 19 after mating. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press

9. Fig. 8 (A) Cortical cells from day 20 Wistar (n = 10), unaffected H ‐ Tx (n = 5) and affected H ‐ Tx (n = 6) foetuses were plated in poly ‐ d ‐ lysine ‐ coated 96 ‐ well plates at a starting density of 1 × 104 cells/ml in supplemented neurobasal medium. Farhad Mashayekhi et al. Brain 2002;125:1859-1874 ©2002 by Oxford University Press