1. Dr Marcus Kaiser The Human Brain Development Project: 27/28 January 2016 Meeting Professor in Neuroinformatics School of Computing Science / Institute of Neuroscience Newcastle University United Kingdom

2. 2 Human Brain Development Silbereis et al. (2016) Neuron www.dynamic-connectome.org

3. 3 Human Brain Development Silbereis et al. (2016) Neuron www.dynamic-connectome.org

4. 4 Human Brain Development Silbereis et al. (2016) Neuron www.dynamic-connectome.org Age at disease onset

5. 5 Scaling up www.dynamic-connectome.org Cortical column: 10k neurons lamination (layer formation) - brain cancer Cortical sheet: 10m neurons gyrification (folding of regions) – epilepsy Cortex: 100m - 10bn neurons changes in connectivity between brain regions - schizophrenia Single-core Multi-core HPC Cloud?

6. Supported by Korean NRF, NIHR, EPSRC, BBSRC, Wellcome Trust, Intel and Royal Society. Team@Newcastle University Luis Peraza PostDoc Frances Hutchings PhD student Michael Mackay PhD student Hamburg University Claus Hilgetag Hamburg University Claus Hilgetag Cambridge University Stephen Eglen Cambridge University Stephen Eglen Glasgow University Glasgow University Peter Uhlhaas IBM / Columbia University Roger Traub IBM / Columbia University Roger Traub São Paulo University Luciano da Fontoura Costa São Paulo University Luciano da Fontoura Costa Nottingham Nottingham Stephen Jackson Reuben O’Dea Jonathan Crofts York University York University Miles Whittington Roman Bauer PostDoc Chris Hayward PhD student Peter Taylor Now faculty Yujiang Wang PostDoc Chris Papasavvas PhD student Jinseop Kim Now faculty Sol Lim PostDoc Chris Thornton PhD student Cheol Han Now faculty